S40285_10017 protein (Stachybotrys chlorohalonata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

S40285_10017

Uncharacterized protein. (151 aa)

Predicted Functional Partners:

S40285_06980

0.843

S40285_09259

0.741

S40285_02464

0.741

S40285_01401

0.638

S40285_00722

0.632

S40285_02607

0.632

S40285_05771

0.606

S40285_02729

0.599

S40285_03669

0.557

S40285_01476

0.549

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_00722	S40285_01401	A0A084QRC2	A0A084QLG2	RPOLD domain-containing protein.	Uncharacterized protein.	0.682
S40285_00722	S40285_02607	A0A084QRC2	A0A084QXL5	RPOLD domain-containing protein.	RPOLD domain-containing protein.	0.802
S40285_00722	S40285_03669	A0A084QRC2	A0A084QTK7	RPOLD domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.632
S40285_00722	S40285_05771	A0A084QRC2	A0A084QAD1	RPOLD domain-containing protein.	Uncharacterized protein.	0.715
S40285_00722	S40285_10017	A0A084QRC2	A0A084QVZ5	RPOLD domain-containing protein.	Uncharacterized protein.	0.632
S40285_01401	S40285_00722	A0A084QLG2	A0A084QRC2	Uncharacterized protein.	RPOLD domain-containing protein.	0.682
S40285_01401	S40285_01476	A0A084QLG2	A0A084QMM2	Uncharacterized protein.	AA_TRNA_LIGASE_II domain-containing protein.	0.423
S40285_01401	S40285_02464	A0A084QLG2	A0A084R0U1	Uncharacterized protein.	Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.751
S40285_01401	S40285_02607	A0A084QLG2	A0A084QXL5	Uncharacterized protein.	RPOLD domain-containing protein.	0.475
S40285_01401	S40285_02729	A0A084QLG2	A0A084QAL4	Uncharacterized protein.	tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.620
S40285_01401	S40285_03669	A0A084QLG2	A0A084QTK7	Uncharacterized protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.638
S40285_01401	S40285_05771	A0A084QLG2	A0A084QAD1	Uncharacterized protein.	Uncharacterized protein.	0.994
S40285_01401	S40285_06980	A0A084QLG2	A0A084QFF1	Uncharacterized protein.	Uncharacterized protein; Belongs to the EF-1-beta/EF-1-delta family.	0.679
S40285_01401	S40285_09259	A0A084QLG2	A0A084Q7Z3	Uncharacterized protein.	Uncharacterized protein.	0.751
S40285_01401	S40285_10017	A0A084QLG2	A0A084QVZ5	Uncharacterized protein.	Uncharacterized protein.	0.638
S40285_01476	S40285_01401	A0A084QMM2	A0A084QLG2	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein.	0.423
S40285_01476	S40285_02729	A0A084QMM2	A0A084QAL4	AA_TRNA_LIGASE_II domain-containing protein.	tRNA-synt_1g domain-containing protein; Belongs to the class-I aminoacyl-tRNA synthetase family.	0.986
S40285_01476	S40285_03669	A0A084QMM2	A0A084QTK7	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein; Belongs to the GST superfamily.	0.549
S40285_01476	S40285_05771	A0A084QMM2	A0A084QAD1	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein.	0.807
S40285_01476	S40285_10017	A0A084QMM2	A0A084QVZ5	AA_TRNA_LIGASE_II domain-containing protein.	Uncharacterized protein.	0.549

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.895

expected number of edges:

26

PPI enrichment p-value:

0.308

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

10 of 457

0.88

0.91

2.14e-06

GO:0006810

Transport

11 of 601

0.8

2.13e-06

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005524

ATP binding

11 of 358

1.02

1.3

4.15e-09

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016021

Integral component of membrane

10 of 815

0.63

0.55

8.22e-05

GO:0005886

Plasma membrane

11 of 1032

0.56

0.49

7.41e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5383

Latent infection - Other responses of Mtb to phagocytosis, and Peptide transport

11 of 65

1.77

4.71

8.58e-17

CL:5385

Latent infection - Other responses of Mtb to phagocytosis, and Peptide transport

9 of 55

1.75

4.02

4.13e-13

CL:5388

Mixed, incl. Peptide transport, and ABC transporter type 1, GsiC-like, N-terminal domain

8 of 43

1.81

3.92

1.05e-11

CL:5389

Mixed, incl. Peptide transport, and ABC transporter type 1, GsiC-like, N-terminal domain

7 of 31

1.89

3.87

1.58e-10

CL:5390

Mixed, incl. Peptide transport, and ABC transporter type 1, GsiC-like, N-terminal domain

4 of 17

1.91

2.22

1.78e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02024

Quorum sensing

11 of 179

1.33

2.37

4.71e-13

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1222499

Latent infection - Other responses of Mtb to phagocytosis

10 of 93

1.57

3.42

4.14e-14

MAP-9635486

Infection with Mycobacterium tuberculosis

10 of 167

1.31

2.25

5.54e-12

MAP-5663205

Infectious disease

10 of 169

1.31

2.24

5.54e-12

MAP-1643685

Disease

10 of 173

1.3

2.2

5.54e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005886

Plasma membrane

10 of 556

0.79

0.76

1.23e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0813

Transport

9 of 246

1.1

1.36

2.21e-07

KW-1003

Cell membrane

9 of 251

1.09

1.34

2.21e-07

KW-1133

Transmembrane helix

9 of 967

0.51

0.37

0.0097

KW-0812

Transmembrane

9 of 967

0.51

0.37

0.0097

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF12911

N-terminal TM domain of oligopeptide transport permease C

5 of 6

2.46

4.12

8.51e-09

PF00528

Binding-protein-dependent transport system inner membrane component

9 of 120

1.41

2.33

1.25e-09

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR025966

Oligopeptide transport permease C-like, N-terminal domain

4 of 5

2.44

2.96

2.15e-06

IPR035906

MetI-like superfamily

9 of 121

1.41

2.27

3.43e-09

IPR000515

ABC transporter type 1, transmembrane domain MetI-like

9 of 121

1.41

2.27

3.43e-09

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