S40285_05451 protein (Stachybotrys chlorohalonata)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

S40285_05451

Uncharacterized protein. (713 aa)

Predicted Functional Partners:

S40285_00790

0.774

S40285_08510

0.725

S40285_03570

0.714

S40285_00186

0.683

S40285_05554

0.660

S40285_01435

0.645

S40285_01440

0.609

S40285_06964

0.609

S40285_10474

0.602

S40285_06570

0.601

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_00186	S40285_00790	A0A084QTU4	A0A084QJP4	Peptidase C50 domain-containing protein.	Protein kinase domain-containing protein.	0.990
S40285_00186	S40285_01440	A0A084QTU4	A0A084QL99	Peptidase C50 domain-containing protein.	Metallophos domain-containing protein.	0.760
S40285_00186	S40285_05451	A0A084QTU4	A0A084QYM8	Peptidase C50 domain-containing protein.	Uncharacterized protein.	0.683
S40285_00186	S40285_06964	A0A084QTU4	A0A084QV35	Peptidase C50 domain-containing protein.	Serine/threonine-protein phosphatase.	0.802
S40285_00186	S40285_08510	A0A084QTU4	A0A084Q7Q6	Peptidase C50 domain-containing protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.954
S40285_00790	S40285_00186	A0A084QJP4	A0A084QTU4	Protein kinase domain-containing protein.	Peptidase C50 domain-containing protein.	0.990
S40285_00790	S40285_01435	A0A084QJP4	A0A084QLF8	Protein kinase domain-containing protein.	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.627
S40285_00790	S40285_01440	A0A084QJP4	A0A084QL99	Protein kinase domain-containing protein.	Metallophos domain-containing protein.	0.929
S40285_00790	S40285_05451	A0A084QJP4	A0A084QYM8	Protein kinase domain-containing protein.	Uncharacterized protein.	0.774
S40285_00790	S40285_05554	A0A084QJP4	A0A084QFH5	Protein kinase domain-containing protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.850
S40285_00790	S40285_06964	A0A084QJP4	A0A084QV35	Protein kinase domain-containing protein.	Serine/threonine-protein phosphatase.	0.967
S40285_00790	S40285_08510	A0A084QJP4	A0A084Q7Q6	Protein kinase domain-containing protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.956
S40285_01435	S40285_00790	A0A084QLF8	A0A084QJP4	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Protein kinase domain-containing protein.	0.627
S40285_01435	S40285_05451	A0A084QLF8	A0A084QYM8	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	Uncharacterized protein.	0.645
S40285_01440	S40285_00186	A0A084QL99	A0A084QTU4	Metallophos domain-containing protein.	Peptidase C50 domain-containing protein.	0.760
S40285_01440	S40285_00790	A0A084QL99	A0A084QJP4	Metallophos domain-containing protein.	Protein kinase domain-containing protein.	0.929
S40285_01440	S40285_05451	A0A084QL99	A0A084QYM8	Metallophos domain-containing protein.	Uncharacterized protein.	0.609
S40285_01440	S40285_08510	A0A084QL99	A0A084Q7Q6	Metallophos domain-containing protein.	Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family.	0.982
S40285_03570	S40285_05451	A0A084QBQ6	A0A084QYM8	Uncharacterized protein.	Uncharacterized protein.	0.714
S40285_03570	S40285_05554	A0A084QBQ6	A0A084QFH5	Uncharacterized protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.561

page 1 of 3

Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.913

expected number of edges:

12

PPI enrichment p-value:

3.76e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009401

Phosphoenolpyruvate-dependent sugar phosphotransferase system

10 of 126

1.44

2.61

2.96e-11

GO:0016310

Phosphorylation

8 of 159

1.24

1.65

2.48e-07

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008982

protein-N(PI)-phosphohistidine-sugar phosphotransferase activity

9 of 87

1.56

2.92

9.44e-11

GO:0016301

Kinase activity

8 of 156

1.25

1.68

1.89e-07

GO:0016740

Transferase activity

10 of 641

0.73

0.69

1.31e-05

GO:0003824

Catalytic activity

11 of 1844

0.32

0.26

0.0225

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1278

0.43

0.32

0.0148

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2472

Starch and sucrose metabolism

11 of 34

2.05

6.79

1.37e-19

CL:2473

Starch and sucrose metabolism

10 of 27

2.11

6.64

8.96e-18

CL:2474

Starch and sucrose metabolism

6 of 22

1.98

3.55

6.82e-09

CL:2517

Mixed, incl. YdjC-like protein, and Glycoside hydrolase, family 4, conserved site

4 of 5

2.44

3.21

6.77e-07

CL:2476

Starch and sucrose metabolism

4 of 17

1.91

2.15

2.71e-05

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

pdc00500

Starch and sucrose metabolism

11 of 69

1.74

4.7

1.60e-17

pdc02060

Phosphotransferase system (PTS)

10 of 100

1.54

3.25

1.34e-13

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005829

Cytosol

10 of 403

0.94

1.04

4.88e-07

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0598

Phosphotransferase system

8 of 49

1.75

3.61

4.69e-11

KW-0813

Transport

9 of 183

1.23

1.77

8.52e-09

KW-0808

Transferase

9 of 519

0.78

0.72

4.86e-05

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF02302

PTS system, Lactose/Cellobiose specific IIB subunit

8 of 26

2.03

4.84

1.56e-12

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR013012

Phosphotransferase system, EIIB component, type 3

8 of 8

2.54

7.14

2.87e-15

IPR036095

PTS system IIB component-like superfamily

8 of 35

1.9

4.17

1.59e-11

IPR003501

Phosphotransferase system, EIIB component, type 2/3

8 of 36

1.89

4.13

1.59e-11

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