S40285_00563 protein (Stachybotrys chlorohalonata)

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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[Homology]

Score

S40285_00563

Uncharacterized protein. (418 aa)

Predicted Functional Partners:

S40285_08051

0.956

S40285_07246

0.927

S40285_01168

0.927

S40285_05876

0.918

S40285_04857

0.914

S40285_02909

0.913

S40285_06575

0.901

S40285_03403

0.895

S40285_06355

0.894

S40285_05034

0.870

Your Current Organism:

Stachybotrys chlorohalonata

NCBI taxonomy Id: 1283841
Other names: S. chlorohalonata IBT 40285, Stachybotrys chlorohalonata IBT 40285

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
S40285_00563	S40285_01168	A0A084R2U2	A0A084QXT6	Uncharacterized protein.	RING-type domain-containing protein.	0.927
S40285_00563	S40285_02909	A0A084R2U2	A0A084QK68	Uncharacterized protein.	Tryptophan synthase.	0.913
S40285_00563	S40285_03403	A0A084R2U2	A0A084QBU9	Uncharacterized protein.	Uncharacterized protein.	0.895
S40285_00563	S40285_04857	A0A084R2U2	A0A084QAA0	Uncharacterized protein.	Uncharacterized protein.	0.914
S40285_00563	S40285_05034	A0A084R2U2	A0A084QFK2	Uncharacterized protein.	Flavodoxin-like domain-containing protein.	0.870
S40285_00563	S40285_05876	A0A084R2U2	A0A084QBJ9	Uncharacterized protein.	Uncharacterized protein.	0.918
S40285_00563	S40285_06355	A0A084R2U2	A0A084QAS1	Uncharacterized protein.	Homoserine dehydrogenase.	0.894
S40285_00563	S40285_06575	A0A084R2U2	A0A084QD66	Uncharacterized protein.	Hcy-binding domain-containing protein.	0.901
S40285_00563	S40285_07246	A0A084R2U2	A0A084QGD9	Uncharacterized protein.	PALP domain-containing protein.	0.927
S40285_00563	S40285_08051	A0A084R2U2	A0A084QEU7	Uncharacterized protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.956
S40285_01168	S40285_00563	A0A084QXT6	A0A084R2U2	RING-type domain-containing protein.	Uncharacterized protein.	0.927
S40285_01168	S40285_02909	A0A084QXT6	A0A084QK68	RING-type domain-containing protein.	Tryptophan synthase.	0.916
S40285_01168	S40285_04857	A0A084QXT6	A0A084QAA0	RING-type domain-containing protein.	Uncharacterized protein.	0.855
S40285_01168	S40285_05034	A0A084QXT6	A0A084QFK2	RING-type domain-containing protein.	Flavodoxin-like domain-containing protein.	0.918
S40285_01168	S40285_05876	A0A084QXT6	A0A084QBJ9	RING-type domain-containing protein.	Uncharacterized protein.	0.944
S40285_01168	S40285_06355	A0A084QXT6	A0A084QAS1	RING-type domain-containing protein.	Homoserine dehydrogenase.	0.717
S40285_01168	S40285_06575	A0A084QXT6	A0A084QD66	RING-type domain-containing protein.	Hcy-binding domain-containing protein.	0.858
S40285_01168	S40285_07246	A0A084QXT6	A0A084QGD9	RING-type domain-containing protein.	PALP domain-containing protein.	0.808
S40285_01168	S40285_08051	A0A084QXT6	A0A084QEU7	RING-type domain-containing protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.813
S40285_02909	S40285_00563	A0A084QK68	A0A084R2U2	Tryptophan synthase.	Uncharacterized protein.	0.913

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.868

expected number of edges:

12

PPI enrichment p-value:

0.000125

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008299

Isoprenoid biosynthetic process

7 of 22

2.47

5.95

7.82e-13

GO:0018343

Protein farnesylation

2 of 2

2.96

1.5

0.0019

GO:0019408

Dolichol biosynthetic process

2 of 4

2.66

1.31

0.0041

GO:1901615

Organic hydroxy compound metabolic process

4 of 105

1.54

1.27

0.0013

GO:0016114

Terpenoid biosynthetic process

2 of 11

2.22

1.02

0.0130

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016765

Transferase activity, transferring alkyl or aryl (other than methyl) groups

8 of 41

2.25

6.02

3.64e-14

GO:0004659

Prenyltransferase activity

6 of 12

2.66

5.89

3.86e-12

GO:0004660

Protein farnesyltransferase activity

2 of 2

2.96

1.47

0.0022

GO:0004337

Geranyltranstransferase activity

2 of 2

2.96

1.47

0.0022

GO:0004161

Dimethylallyltranstransferase activity

2 of 2

2.96

1.47

0.0022

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005965

Protein farnesyltransferase complex

2 of 2

2.96

1.27

0.0051

GO:1990234

Transferase complex

5 of 345

1.12

0.78

0.0074

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9992

Isoprenoid biosynthetic process, and Protein farnesylation

9 of 18

2.66

9.3

1.21e-19

CL:9995

Prenyltransferase activity

6 of 6

2.96

6.98

8.26e-14

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00900

Terpenoid backbone biosynthesis

8 of 30

2.39

7.12

4.13e-16

map01110

Biosynthesis of secondary metabolites

8 of 447

1.22

1.61

1.61e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-446199

Synthesis of Dolichyl-phosphate

3 of 7

2.6

2.14

0.00011

MAP-446219

Synthesis of substrates in N-glycan biosythesis

3 of 22

2.1

1.55

0.0010

MAP-191273

Cholesterol biosynthesis

3 of 24

2.06

1.54

0.0010

MAP-446193

Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

3 of 39

1.85

1.3

0.0025

MAP-2142789

Ubiquinol biosynthesis

2 of 8

2.36

1.15

0.0074

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1904423

Dehydrodolichyl diphosphate synthase complex

2 of 2

2.96

1.21

0.0064

GOCC:0005965

Protein farnesyltransferase complex

2 of 2

2.96

1.21

0.0064

GOCC:1990234

Transferase complex

5 of 374

1.09

0.74

0.0091

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0808

Transferase

5 of 336

1.14

0.86

0.0037

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00348

Polyprenyl synthetase

3 of 3

2.96

2.61

1.78e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR033749

Polyprenyl synthetase, conserved site

3 of 3

2.96

2.36

5.09e-05

IPR000092

Polyprenyl synthetase

3 of 3

2.96

2.36

5.09e-05

IPR008949

Isoprenoid synthase domain superfamily

3 of 5

2.74

2.34

5.09e-05

IPR036424

Decaprenyl diphosphate synthase-like superfamily

2 of 2

2.96

1.31

0.0043

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