| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC95256.1 | nrdG | SHYC_02255 | SHYC_00465 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.523 |
| AJC95256.1 | queC | SHYC_02255 | SHYC_10165 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). | 0.672 |
| AJC95256.1 | queD | SHYC_02255 | SHYC_10170 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| AJC95256.1 | queF | SHYC_02255 | SHYC_10080 | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.557 |
| guaA | nrdE-2 | SHYC_11770 | SHYC_10065 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.464 |
| guaA | nrdG | SHYC_11770 | SHYC_00465 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.411 |
| guaA | queF | SHYC_11770 | SHYC_10080 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.488 |
| ldh-1 | nrdD | SHYC_00455 | SHYC_00460 | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
| ldh-1 | nrdG | SHYC_00455 | SHYC_00465 | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.429 |
| nrdD | ldh-1 | SHYC_00460 | SHYC_00455 | Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | 0.428 |
| nrdD | nrdG | SHYC_00460 | SHYC_00465 | Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.995 |
| nrdE-2 | guaA | SHYC_10065 | SHYC_11770 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.464 |
| nrdE-2 | nrdG | SHYC_10065 | SHYC_00465 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 0.436 |
| nrdE-2 | nrdI-2 | SHYC_10065 | SHYC_10070 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Ribonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function. | 0.993 |
| nrdG | AJC95256.1 | SHYC_00465 | SHYC_02255 | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | 6-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.523 |
| nrdG | guaA | SHYC_00465 | SHYC_11770 | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.411 |
| nrdG | ldh-1 | SHYC_00465 | SHYC_00455 | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | 0.429 |
| nrdG | nrdD | SHYC_00465 | SHYC_00460 | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Ribonucleoside-triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.995 |
| nrdG | nrdE-2 | SHYC_00465 | SHYC_10065 | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.436 |
| nrdG | nrdI-2 | SHYC_00465 | SHYC_10070 | Ribonucleoside-triphosphate reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. | Ribonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function. | 0.518 |