| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC95402.1 | AJC95404.1 | SHYC_02990 | SHYC_03000 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | BioY family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
| AJC95402.1 | nanA | SHYC_02990 | SHYC_02985 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.707 |
| AJC95402.1 | nanK | SHYC_02990 | SHYC_02995 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylmannosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.871 |
| AJC95402.1 | nanT | SHYC_02990 | SHYC_02980 | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Putative sialic acid transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.435 |
| AJC95404.1 | AJC95402.1 | SHYC_03000 | SHYC_02990 | BioY family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.773 |
| AJC95404.1 | nanA | SHYC_03000 | SHYC_02985 | BioY family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.455 |
| AJC95404.1 | nanK | SHYC_03000 | SHYC_02995 | BioY family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylmannosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.780 |
| arcA | nanA | SHYC_00860 | SHYC_02985 | Arginine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.463 |
| aroF | nanA | SHYC_05950 | SHYC_02985 | 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate; Derived by automated computational analysis using gene prediction method: Protein Homology. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.519 |
| aroF | rpsO | SHYC_05950 | SHYC_08025 | 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. | 0.534 |
| dapB | nanA | SHYC_07500 | SHYC_02985 | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.634 |
| gatC | nanA | SHYC_04315 | SHYC_02985 | glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 0.499 |
| nanA | AJC95402.1 | SHYC_02985 | SHYC_02990 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.707 |
| nanA | AJC95404.1 | SHYC_02985 | SHYC_03000 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | BioY family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.455 |
| nanA | arcA | SHYC_02985 | SHYC_00860 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | Arginine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.463 |
| nanA | aroF | SHYC_02985 | SHYC_05950 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Catalyzes the formation of 3-deoxy-D-aribino-hept-2-ulosonate 7-phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate and the formation of prephenate from chorismate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.519 |
| nanA | dapB | SHYC_02985 | SHYC_07500 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. | 0.634 |
| nanA | gatC | SHYC_02985 | SHYC_04315 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. | 0.499 |
| nanA | nanE | SHYC_02985 | SHYC_10805 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | N-acetylmannosamine-6-phosphate 2-epimerase; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.877 |
| nanA | nanK | SHYC_02985 | SHYC_02995 | N-acetylneuraminate lyase; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate. | N-acetylmannosamine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.962 |