STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
lacRLactose phosphotransferase system repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)    
Predicted Functional Partners:
lacC
Tagatose-6-phosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.888
fruA
PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.823
AJC95164.1
PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.808
fruK
1-phosphofructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
 
  
 0.807
lacA
Galactose-6-phosphate isomerase subunit LacA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.766
lacB
Galactose-6-phosphate isomerase subunit LacB; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.763
lacD
Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.654
lacE
PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.620
lacF
PTS system lactose-specific transporter subunit IIA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.613
AJC95471.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.453
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
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