Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdpPyrimidine-nucleoside phosphorylase; Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (433 aa)    
Predicted Functional Partners:
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family.
 
 
 0.973
tdk
Thymidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.944
udk
Uridine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.944
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
    
 0.927
AJC94931.1
Cytidine deaminase; Reclaims exogenous and endogenous cytidine and 2'-deoxycytidine molecules for UMP synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.922
pyrR
Pyrimidine regulatory protein PyrR/uracil phosphoribosyltransferase; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily.
     
 0.916
psuG
Pseudouridine-5'-phosphate glycosidase; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family.
    
 0.903
AJC96576.1
2', 3'-cyclic nucleotide 2'-phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family.
    
  0.903
deoB-1
Phosphopentomutase; Catalyzes the transfer of phosphate between the C1 and C5 carbons of pentose; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.883
deoB-2
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
 
 0.883
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.