| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC95681.1 | AJC95965.1 | SHYC_04460 | SHYC_06125 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.931 |
| AJC95681.1 | ackA | SHYC_04460 | SHYC_06080 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | 0.930 |
| AJC95681.1 | ilvH | SHYC_04460 | SHYC_04010 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.988 |
| AJC95681.1 | korA | SHYC_04460 | SHYC_07930 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.948 |
| AJC95681.1 | ldh-1 | SHYC_04460 | SHYC_00455 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | 0.924 |
| AJC95681.1 | ldh-2 | SHYC_04460 | SHYC_05820 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.924 |
| AJC95681.1 | leuA | SHYC_04460 | SHYC_04000 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.938 |
| AJC95681.1 | pflB | SHYC_04460 | SHYC_02345 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.921 |
| AJC95681.1 | pyc | SHYC_04460 | SHYC_08740 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.924 |
| AJC95681.1 | pyk | SHYC_04460 | SHYC_06145 | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.934 |
| AJC95965.1 | AJC95681.1 | SHYC_06125 | SHYC_04460 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.931 |
| AJC95965.1 | ilvH | SHYC_06125 | SHYC_04010 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.827 |
| AJC95965.1 | korA | SHYC_06125 | SHYC_07930 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.952 |
| AJC95965.1 | ldh-1 | SHYC_06125 | SHYC_00455 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | L-lactate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LDH/MDH superfamily. | 0.939 |
| AJC95965.1 | ldh-2 | SHYC_06125 | SHYC_05820 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.939 |
| AJC95965.1 | leuA | SHYC_06125 | SHYC_04000 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.835 |
| AJC95965.1 | pflB | SHYC_06125 | SHYC_02345 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Formate acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.913 |
| AJC95965.1 | pyc | SHYC_06125 | SHYC_08740 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.946 |
| AJC95965.1 | pyk | SHYC_06125 | SHYC_06145 | NAD-dependent malic enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. | Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.985 |
| ackA | AJC95681.1 | SHYC_06080 | SHYC_04460 | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. | Pyruvate oxidase; Catalyzes the formation of acetyl phosphate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. | 0.930 |