| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC95687.1 | AJC95689.1 | SHYC_04490 | SHYC_04500 | Membrane bound metal dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNAse G and E associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0374 family. | 0.692 |
| AJC95687.1 | AJC95690.1 | SHYC_04490 | SHYC_04505 | Membrane bound metal dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.605 |
| AJC95687.1 | mutY | SHYC_04490 | SHYC_04495 | Membrane bound metal dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.751 |
| AJC95689.1 | AJC95687.1 | SHYC_04500 | SHYC_04490 | RNAse G and E associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0374 family. | Membrane bound metal dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.692 |
| AJC95689.1 | AJC95690.1 | SHYC_04500 | SHYC_04505 | RNAse G and E associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0374 family. | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.604 |
| AJC95689.1 | mutY | SHYC_04500 | SHYC_04495 | RNAse G and E associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0374 family. | Adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.812 |
| AJC95690.1 | AJC95687.1 | SHYC_04505 | SHYC_04490 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Membrane bound metal dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.605 |
| AJC95690.1 | AJC95689.1 | SHYC_04505 | SHYC_04500 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | RNAse G and E associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0374 family. | 0.604 |
| AJC95690.1 | mutY | SHYC_04505 | SHYC_04495 | ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.666 |
| aspS | mutY | SHYC_06420 | SHYC_04495 | aspartyl-tRNA synthase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | Adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.536 |
| aspS | recJ | SHYC_06420 | SHYC_06390 | aspartyl-tRNA synthase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. | single-stranded-DNA exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.522 |
| dnaN | mutL | SHYC_00010 | SHYC_07895 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.929 |
| dnaN | mutY | SHYC_00010 | SHYC_04495 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.753 |
| dnaN | polA | SHYC_00010 | SHYC_06170 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.983 |
| dnaN | polX | SHYC_00010 | SHYC_08640 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase/3'-5' exonuclease PolX; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.605 |
| dnaN | recJ | SHYC_00010 | SHYC_06390 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | single-stranded-DNA exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.527 |
| mutL | dnaN | SHYC_07895 | SHYC_00010 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.929 |
| mutL | mutM | SHYC_07895 | SHYC_06175 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. Belongs to the FPG family. | 0.521 |
| mutL | mutY | SHYC_07895 | SHYC_04495 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | Adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.537 |
| mutL | polA | SHYC_07895 | SHYC_06170 | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.855 |