Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AJC95710.1Signal transduction histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)    
Predicted Functional Partners:
AJC95711.1
Response regulator protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.986
nreC
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.912
vraR
Response regulator protein VraR; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.911
AJC96297.1
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.902
AJC95709.1
RluD subfamily ribosomal large subunit pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.772
AJC96298.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.765
prkC
Serine/threonine-protein kinase PrkC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.710
rsmB
Ribosomal RNA small subunit methyltransferase B; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.631
mprF
Phosphatidylglycerol lysyltransferase; Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms.
   
  
 0.552
AJC95943.1
Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.516
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.