STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
derGTP-binding protein Der; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (436 aa)    
Predicted Functional Partners:
cmk
Cytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.987
gpsA
Glycerol-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.
 
  
 0.986
rluB
Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; ribosomal large subunit pseudouridine synthase B; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.784
rpsA
30S ribosomal protein S1; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.759
ftsY
Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).
 
   
 0.690
rsuA
Ribosomal small subunit pseudouridine synthase A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family.
 
  
 0.663
ffh
Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily.
 
  
 0.641
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
 
  
 0.614
ansB
Asparaginase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.583
typA
GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.548
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.