Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
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[Homology]
Score
recUHolliday junction resolvase; Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation; Belongs to the RecU family. (208 aa)    
Predicted Functional Partners:
gpsB
Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
 
   
 0.918
AJC96197.1
Transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.890
AJC96275.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.760
AJC96200.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0398 family.
  
    0.669
AJC96199.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.660
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
   
 0.653
dnaB-2
Chromosome replication protein DnaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.651
dnaI
Primosomal protein DnaI; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.637
recJ
single-stranded-DNA exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.621
AJC96471.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.607
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
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