| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC96207.1 | AJC96208.1 | SHYC_07330 | SHYC_07335 | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.679 |
| AJC96207.1 | AJC96210.1 | SHYC_07330 | SHYC_07345 | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | 0.665 |
| AJC96207.1 | cvfC | SHYC_07330 | SHYC_07340 | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.725 |
| AJC96207.1 | queF | SHYC_07330 | SHYC_10080 | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | 0.627 |
| AJC96207.1 | rnhA | SHYC_07330 | SHYC_07325 | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Ribonuclease H-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.493 |
| AJC96207.1 | thyA | SHYC_07330 | SHYC_07350 | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.415 |
| AJC96208.1 | AJC96207.1 | SHYC_07335 | SHYC_07330 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.679 |
| AJC96208.1 | AJC96210.1 | SHYC_07335 | SHYC_07345 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | 0.836 |
| AJC96208.1 | cvfC | SHYC_07335 | SHYC_07340 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.857 |
| AJC96208.1 | thyA | SHYC_07335 | SHYC_07350 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.697 |
| AJC96210.1 | AJC96207.1 | SHYC_07345 | SHYC_07330 | Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.665 |
| AJC96210.1 | AJC96208.1 | SHYC_07345 | SHYC_07335 | Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.836 |
| AJC96210.1 | cvfC | SHYC_07345 | SHYC_07340 | Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.873 |
| AJC96210.1 | thyA | SHYC_07345 | SHYC_07350 | Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.714 |
| cvfC | AJC96207.1 | SHYC_07340 | SHYC_07330 | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.725 |
| cvfC | AJC96208.1 | SHYC_07340 | SHYC_07335 | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.857 |
| cvfC | AJC96210.1 | SHYC_07340 | SHYC_07345 | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. | 0.873 |
| cvfC | thyA | SHYC_07340 | SHYC_07350 | Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.703 |
| queF | AJC96207.1 | SHYC_10080 | SHYC_07330 | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.627 |
| rnhA | AJC96207.1 | SHYC_07325 | SHYC_07330 | Ribonuclease H-like protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. | 0.493 |