STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AJC96210.1Disulfide isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0403 family. (146 aa)    
Predicted Functional Partners:
cvfC
Virulence factor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.879
AJC96208.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.849
bshC
BshC family protein; Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH.
  
   
 0.779
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
       0.774
bshA
N-acetyl-alpha-D-glucosaminyl L-malate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.770
ypdA
Pyridine nucleotide-disulfide oxidoreductase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.755
AJC96207.1
YhhQ family membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.
       0.733
ytxJ
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.732
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.726
fakB2
DegV family protein FakB2; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.724
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.