| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC95164.1 | AJC96771.1 | SHYC_01790 | SHYC_10210 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
| AJC95164.1 | fruA | SHYC_01790 | SHYC_10200 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
| AJC95164.1 | lacA | SHYC_01790 | SHYC_03350 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Galactose-6-phosphate isomerase subunit LacA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| AJC95164.1 | lacB | SHYC_01790 | SHYC_03355 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Galactose-6-phosphate isomerase subunit LacB; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| AJC95164.1 | lacC | SHYC_01790 | SHYC_07525 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-6-phosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.993 |
| AJC95164.1 | lacD | SHYC_01790 | SHYC_03360 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.417 |
| AJC95164.1 | lacE | SHYC_01790 | SHYC_03370 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.613 |
| AJC95164.1 | lacF | SHYC_01790 | SHYC_03365 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system lactose-specific transporter subunit IIA; Catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; protein IIA transfers a phosphoryl group to IIB which then transfers the phosphoryl group to the sugar; IIC forms the translocation channel for the sugar uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.545 |
| AJC95164.1 | lacR | SHYC_01790 | SHYC_03345 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | Lactose phosphotransferase system repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.752 |
| AJC95164.1 | pfkA | SHYC_01790 | SHYC_06140 | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.519 |
| AJC96771.1 | AJC95164.1 | SHYC_10210 | SHYC_01790 | DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.819 |
| AJC96771.1 | fruA | SHYC_10210 | SHYC_10200 | DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| AJC96771.1 | lacC | SHYC_10210 | SHYC_07525 | DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-6-phosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.844 |
| fruA | AJC95164.1 | SHYC_10200 | SHYC_01790 | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS transporter subunit IIABC; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.992 |
| fruA | AJC96771.1 | SHYC_10200 | SHYC_10210 | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | DeoR faimly transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.976 |
| fruA | lacA | SHYC_10200 | SHYC_03350 | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | Galactose-6-phosphate isomerase subunit LacA; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| fruA | lacB | SHYC_10200 | SHYC_03355 | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | Galactose-6-phosphate isomerase subunit LacB; Catalyzes the interconversion of galactose 6-phosphate to tagatose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| fruA | lacC | SHYC_10200 | SHYC_07525 | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-6-phosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. LacC subfamily. | 0.993 |
| fruA | lacD | SHYC_10200 | SHYC_03360 | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tagatose-bisphosphate aldolase; Catalyzes the reversible reaction of dihydroxyacetone phosphate with glyceraldehyde 3-phosphate to produce tagatose 1,6-bisphosphate; in Streptococcus pyogenes there are two paralogs of tagatose-bisphosphate aldolase, encoded by lacD1 and lacD2; expression of lacD1 is highly regulated by environmental conditions while lacD2 specializes in an efficient utilization of carbohydrate sources; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.447 |
| fruA | lacE | SHYC_10200 | SHYC_03370 | PTS system fructose-specific IIABC component; Derived by automated computational analysis using gene prediction method: Protein Homology. | PTS system lactose-specific transporter subunits IICB; Phosphoenolpyruvate-dependent sugar phosphotransferase system; catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane; IIB is phosphorylated by IIA and then transfers the phosphoryl group to the sugar; IIC forms the translocation channel; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.613 |