| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC95379.1 | AJC96554.1 | SHYC_02875 | SHYC_09095 | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | LytR family transcriptional regulator. | 0.920 |
| AJC95379.1 | dltA | SHYC_02875 | SHYC_09620 | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | 0.900 |
| AJC95379.1 | dltB | SHYC_02875 | SHYC_09615 | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanine transport protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.901 |
| AJC95379.1 | dltC | SHYC_02875 | SHYC_09610 | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.900 |
| AJC95379.1 | dltD | SHYC_02875 | SHYC_09605 | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Poly D-alanine transfer protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| AJC95379.1 | msrR | SHYC_02875 | SHYC_07580 | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulatory protein MsrR; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
| AJC95379.1 | tagO | SHYC_02875 | SHYC_09995 | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | Putative undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.504 |
| AJC96554.1 | AJC95379.1 | SHYC_09095 | SHYC_02875 | LytR family transcriptional regulator. | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.920 |
| AJC96554.1 | dltA | SHYC_09095 | SHYC_09620 | LytR family transcriptional regulator. | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | 0.900 |
| AJC96554.1 | dltB | SHYC_09095 | SHYC_09615 | LytR family transcriptional regulator. | D-alanine transport protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.901 |
| AJC96554.1 | dltC | SHYC_09095 | SHYC_09610 | LytR family transcriptional regulator. | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.900 |
| AJC96554.1 | dltD | SHYC_09095 | SHYC_09605 | LytR family transcriptional regulator. | Poly D-alanine transfer protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| AJC96554.1 | msrR | SHYC_09095 | SHYC_07580 | LytR family transcriptional regulator. | Regulatory protein MsrR; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.928 |
| AJC96554.1 | tagO | SHYC_09095 | SHYC_09995 | LytR family transcriptional regulator. | Putative undecaprenyl-phosphate N-acetylglucosaminyl 1-phosphate transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.495 |
| codY | msrR | SHYC_08125 | SHYC_07580 | GTP-sensing transcriptional pleiotropic repressor CodY; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | Regulatory protein MsrR; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.406 |
| dltA | AJC95379.1 | SHYC_09620 | SHYC_02875 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | LytR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.900 |
| dltA | AJC96554.1 | SHYC_09620 | SHYC_09095 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | LytR family transcriptional regulator. | 0.900 |
| dltA | dltB | SHYC_09620 | SHYC_09615 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | D-alanine transport protein DltB; Could be involved in the transport of activated D-alanine through the membrane. | 0.999 |
| dltA | dltC | SHYC_09620 | SHYC_09610 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | D-alanine--poly(phosphoribitol) ligase subunit 2; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.999 |
| dltA | dltD | SHYC_09620 | SHYC_09605 | D-alanine--poly(phosphoribitol) ligase subunit 1; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to [...] | Poly D-alanine transfer protein DltD; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
