Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
sbcDExonuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. (372 aa)    
Predicted Functional Partners:
sbcC
Exonuclease SbcCD subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.997
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
   
 0.876
AJC96274.1
Cytochrome C biogenesis protein CcdC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.721
addA
ATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase.
 
  
 0.687
addB
ATP-dependent helicase/nuclease subunit B; ATP-dependent DNA helicase.
 
  
 0.665
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.645
recQ-1
ATP-dependent DNA helicase RecQ-1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.608
recQ-2
ATP-dependent DNA helicase RecQ-2; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.608
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
  
 0.569
recJ
single-stranded-DNA exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.536
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
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