| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC96218.1 | AJC96454.1 | SHYC_07385 | SHYC_08595 | Carboxy-terminal processing proteinase CtpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.437 |
| AJC96454.1 | AJC96218.1 | SHYC_08595 | SHYC_07385 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Carboxy-terminal processing proteinase CtpA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. | 0.437 |
| AJC96454.1 | ltaS | SHYC_08595 | SHYC_10130 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycerol phosphate lipoteichoic acid synthase; Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Belongs to the LTA synthase family. | 0.451 |
| AJC96454.1 | murI | SHYC_08595 | SHYC_08605 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.864 |
| AJC96454.1 | rdgB | SHYC_08595 | SHYC_08600 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.960 |
| AJC96454.1 | sdhA-2 | SHYC_08595 | SHYC_08615 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.678 |
| AJC96454.1 | sdhB-2 | SHYC_08595 | SHYC_08610 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.677 |
| AJC96454.1 | sdhC | SHYC_08595 | SHYC_08620 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase cytochrome b558 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
| ltaS | AJC96454.1 | SHYC_10130 | SHYC_08595 | Glycerol phosphate lipoteichoic acid synthase; Catalyzes the polymerization of lipoteichoic acid (LTA) polyglycerol phosphate, a reaction that presumably uses phosphatidylglycerol (PG) as substrate. Belongs to the LTA synthase family. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.451 |
| murI | AJC96454.1 | SHYC_08605 | SHYC_08595 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.864 |
| murI | rdgB | SHYC_08605 | SHYC_08600 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.986 |
| murI | sdhA-2 | SHYC_08605 | SHYC_08615 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.493 |
| murI | sdhB-2 | SHYC_08605 | SHYC_08610 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.512 |
| murI | sdhC | SHYC_08605 | SHYC_08620 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Succinate dehydrogenase cytochrome b558 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
| rdgB | AJC96454.1 | SHYC_08600 | SHYC_08595 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.960 |
| rdgB | murI | SHYC_08600 | SHYC_08605 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.986 |
| rdgB | sdhA-2 | SHYC_08600 | SHYC_08615 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.669 |
| rdgB | sdhB-2 | SHYC_08600 | SHYC_08610 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.669 |
| rdgB | sdhC | SHYC_08600 | SHYC_08620 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Succinate dehydrogenase cytochrome b558 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.696 |
| sdhA-2 | AJC96454.1 | SHYC_08615 | SHYC_08595 | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.678 |