| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC94986.1 | AJC96454.1 | SHYC_00825 | SHYC_08595 | Tributyrin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.565 |
| AJC96454.1 | AJC94986.1 | SHYC_08595 | SHYC_00825 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tributyrin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.565 |
| AJC96454.1 | ahpC | SHYC_08595 | SHYC_11825 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | 0.469 |
| AJC96454.1 | murI | SHYC_08595 | SHYC_08605 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.868 |
| AJC96454.1 | rdgB | SHYC_08595 | SHYC_08600 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.966 |
| AJC96454.1 | ribBA | SHYC_08595 | SHYC_05790 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3,4-dihydroxy-2-butanone 4- phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.478 |
| AJC96454.1 | ribD | SHYC_08595 | SHYC_05780 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.478 |
| AJC96454.1 | sdhA-2 | SHYC_08595 | SHYC_08615 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.692 |
| AJC96454.1 | sdhB-2 | SHYC_08595 | SHYC_08610 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.693 |
| AJC96454.1 | sdhC | SHYC_08595 | SHYC_08620 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Succinate dehydrogenase cytochrome b558 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.619 |
| AJC96454.1 | uvrC | SHYC_08595 | SHYC_08625 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.496 |
| ahpC | AJC96454.1 | SHYC_11825 | SHYC_08595 | Alkyl hydroperoxide reductase subunit C; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.469 |
| murI | AJC96454.1 | SHYC_08605 | SHYC_08595 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.868 |
| murI | rdgB | SHYC_08605 | SHYC_08600 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.986 |
| murI | ribD | SHYC_08605 | SHYC_05780 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.505 |
| murI | sdhA-2 | SHYC_08605 | SHYC_08615 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.643 |
| murI | sdhB-2 | SHYC_08605 | SHYC_08610 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.641 |
| murI | sdhC | SHYC_08605 | SHYC_08620 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Succinate dehydrogenase cytochrome b558 subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.619 |
| murI | uvrC | SHYC_08605 | SHYC_08625 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.756 |
| rdgB | AJC96454.1 | SHYC_08600 | SHYC_08595 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.966 |
