Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
AJC96601.1CoiA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)    
Predicted Functional Partners:
pepF-2
Oligoendopeptidase F; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.778
AJC95955.1
Adenine DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.730
dprA
Putative DNA processing factor DprA(SMF); Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.637
gpsB
Cell division protein GpsB; Divisome component that associates with the complex late in its assembly, after the Z-ring is formed, and is dependent on DivIC and PBP2B for its recruitment to the divisome. Together with EzrA, is a key component of the system that regulates PBP1 localization during cell cycle progression. Its main role could be the removal of PBP1 from the cell pole after pole maturation is completed. Also contributes to the recruitment of PBP1 to the division complex. Not essential for septum formation.
  
     0.626
mecA
Adapter protein MecA; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis.
       0.618
AJC96040.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0473 family.
  
     0.615
comEA
ComEA family DNA binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.612
ezrA
Septation ring formation regulator EzrA; Negative regulator of FtsZ ring formation; modulates the frequency and position of FtsZ ring formation. Inhibits FtsZ ring formation at polar sites. Interacts either with FtsZ or with one of its binding partners to promote depolymerization; Belongs to the EzrA family.
  
     0.601
comFA
Competence protein ComFA; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.559
AJC96275.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.554
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
Server load: medium (44%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.