Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
cdrCoA-disulfide reductase; Catalyzes specifically the NADPH-dependent reduction of coenzyme A disulfide; Belongs to the class-III pyridine nucleotide-disulfide oxidoreductase family. (440 aa)    
Predicted Functional Partners:
AJC95052.1
DsrE/DsrF/DrsH-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
  
 0.982
AJC96615.1
Cof family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.854
AJC96614.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.737
AJC95381.1
Putative formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.694
sodA
Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
  
 
 0.599
nirD
Nitrite reductase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.553
tpx
Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
      
 0.525
clpB
ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
 
 0.488
AJC95318.1
Copper resistance CopC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.483
spxA
Regulatory protein Spx; Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development- promoting processes and to increase transcription of genes involved in thiol homeostasis, during periods of extreme stress. Belongs to the ArsC family. Spx subfamily.
      
 0.478
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
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