Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
addAATP-dependent helicase/nuclease subunit A; ATP-dependent DNA helicase. (1212 aa)    
Predicted Functional Partners:
addB
ATP-dependent helicase/nuclease subunit B; ATP-dependent DNA helicase.
 
 
 0.999
AJC96618.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.756
sipB
Signal peptidase IB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S26 family.
  
    0.733
dinG
DnaQ family exonuclease/DinG family helicase; 3'-5' exonuclease.
  
  
 0.691
pcrA
ATP-dependent DNA helicase PcrA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
0.687
sbcD
Exonuclease SbcCD subunit D; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.
 
  
 0.687
trmK
tRNA (adenine(22)-N(1))-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.643
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
   
 0.633
AJC96617.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.624
sbcC
Exonuclease SbcCD subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.592
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
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