Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
AJC96801.1HesA/MoeB/ThiF family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)    
Predicted Functional Partners:
thiS
Sulfur carrier protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.987
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
  
 0.979
thiE-2
Thiamine monophosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.920
moaE
Molybdopterin synthase subunit 2; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.913
thiI
Putative tRNA sulfurtransferase; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
    
 0.912
AJC96800.1
YebC/PmpR family DNA-binding regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.756
moaD
Molybdopterin synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.740
moeA
Molybdopterin molybdenumtransferase; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family.
 
  
 0.699
AJC96805.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.643
AJC95052.1
DsrE/DsrF/DrsH-like family protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sulfur carrier protein TusA family.
     
 0.590
Your Current Organism:
Staphylococcus hyicus
NCBI taxonomy Id: 1284
Other names: ATCC 11249, CCM 2368, CCUG 6509, CIP 81.58, DSM 20459, JCM 2423, LMG 13352, LMG:13352, Micrococcus hyicus, NCTC 10350, S. hyicus, Staphylococcus hyicus hyicus, Staphylococcus hyicus subsp. hyicus
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