| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AJC96977.1 | spoVG | SHYC_11340 | SHYC_11255 | Orn Lys Arg decarboxylase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulatory protein SpoVG; Could be involved in septation. | 0.491 |
| glmU | ispE | SHYC_11250 | SHYC_11270 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | 0.458 |
| glmU | purR | SHYC_11250 | SHYC_11265 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.656 |
| glmU | spoVG | SHYC_11250 | SHYC_11255 | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | Regulatory protein SpoVG; Could be involved in septation. | 0.477 |
| ispE | glmU | SHYC_11270 | SHYC_11250 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.458 |
| ispE | purR | SHYC_11270 | SHYC_11265 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.861 |
| ispE | spoVG | SHYC_11270 | SHYC_11255 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Regulatory protein SpoVG; Could be involved in septation. | 0.570 |
| ispE | yabJ | SHYC_11270 | SHYC_11260 | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | Enamine/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.840 |
| pth | spoVG | SHYC_11235 | SHYC_11255 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Regulatory protein SpoVG; Could be involved in septation. | 0.562 |
| purR | glmU | SHYC_11265 | SHYC_11250 | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.656 |
| purR | ispE | SHYC_11265 | SHYC_11270 | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | 0.861 |
| purR | spoVG | SHYC_11265 | SHYC_11255 | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Regulatory protein SpoVG; Could be involved in septation. | 0.837 |
| purR | yabJ | SHYC_11265 | SHYC_11260 | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | Enamine/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.881 |
| rsbW | spoVG | SHYC_03935 | SHYC_11255 | Serine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | Regulatory protein SpoVG; Could be involved in septation. | 0.421 |
| spoVG | AJC96977.1 | SHYC_11255 | SHYC_11340 | Regulatory protein SpoVG; Could be involved in septation. | Orn Lys Arg decarboxylase family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.491 |
| spoVG | glmU | SHYC_11255 | SHYC_11250 | Regulatory protein SpoVG; Could be involved in septation. | Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.477 |
| spoVG | ispE | SHYC_11255 | SHYC_11270 | Regulatory protein SpoVG; Could be involved in septation. | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol; Belongs to the GHMP kinase family. IspE subfamily. | 0.570 |
| spoVG | pth | SHYC_11255 | SHYC_11235 | Regulatory protein SpoVG; Could be involved in septation. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.562 |
| spoVG | purR | SHYC_11255 | SHYC_11265 | Regulatory protein SpoVG; Could be involved in septation. | Purine operon repressor; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.837 |
| spoVG | rsbW | SHYC_11255 | SHYC_03935 | Regulatory protein SpoVG; Could be involved in septation. | Serine-protein kinase RsbW; Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B). | 0.421 |