STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tmkThymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (205 aa)    
Predicted Functional Partners:
WA1_10395
DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.857
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.838
WA1_33620
HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
  0.836
WA1_01915
Bifunctional metallophosphatase/5'-nucleotidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.817
coaX
Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
   
   0.736
WA1_19615
Thymidylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.718
dcd
dCTP deaminase; Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.696
WA1_42310
Antibiotic biosynthesis monooxygenase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.696
WA1_46400
Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family.
  
 
 0.695
WA1_23815
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
  0.694
Your Current Organism:
Scytonema hofmannii
NCBI taxonomy Id: 128403
Other names: S. hofmannii PCC 7110, Scytonema hofmannii PCC 7110, Scytonema sp. ATCC 29171, Scytonema sp. PCC 7110
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