STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
WA1_14320Circadian clock protein KaiA; Component of the kaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The kaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it enhances the phosphorylation status of kaiC. In contrast, the presence of kaiB in the complex decreases the phosphorylation status of kaiC, suggesting that kaiB acts by antagonizing the interaction between kaiA and kaiC. A kaiA dimer is sufficient to enhance kaiC he [...] (102 aa)    
Predicted Functional Partners:
kaiC
Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
 
 
 
 0.980
kaiB
Circadian clock protein KaiB; Component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. The KaiABC complex may act as a promoter-non-specific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction. In the complex, it decreases the phosphorylation status of KaiC. It has no effect on KaiC by itself, but instead needs the presence of both KaiA and KaiC, suggesting that it acts by antagonizing the interaction between KaiA and KaiC; Belongs to the KaiB family.
 
 
 
 0.962
WA1_42385
Circadian clock protein KaiB; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 
 0.918
WA1_04470
Circadian clock protein KaiB; Decreases the phosphorylation of KaiC, a component of the main circadian regulator in cyanobacteria; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.906
WA1_07645
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.772
WA1_28315
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.770
WA1_12335
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.764
WA1_10085
AbrB family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.762
WA1_03455
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.756
WA1_29255
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.755
Your Current Organism:
Scytonema hofmannii
NCBI taxonomy Id: 128403
Other names: S. hofmannii PCC 7110, Scytonema hofmannii PCC 7110, Scytonema sp. ATCC 29171, Scytonema sp. PCC 7110
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