SDE10666.1 protein (Niabella drilacis) - STRING interaction network

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second shell of interactors

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

SDE10666.1

TonB-linked outer membrane protein, SusC/RagA family. (1143 aa)

Predicted Functional Partners:

SDE10641.1

0.933

SDD25735.1

0.773

SDC99404.1

0.772

SDE06192.1

0.768

SDD34295.1

0.767

SDC19635.1

0.766

SDC33446.1

0.763

SDC19175.1

0.757

SDC50378.1

0.755

SDC59337.1

0.748

Your Current Organism:

Niabella drilacis

NCBI taxonomy Id: 1285928
Other names: CCM 8410, DSM 25811, LMG 26954, LMG:26954, N. drilacis, Niabella drilacis Glaeser et al. 2013, Niabella sp. E90, strain E90

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDC19175.1	SDC33446.1	SAMN04487894_101562	SAMN04487894_10270	Starch-binding associating with outer membrane.	Starch-binding associating with outer membrane.	0.647
SDC19175.1	SDE10666.1	SAMN04487894_101562	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.757
SDC19635.1	SDE10666.1	SAMN04487894_101574	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.766
SDC33446.1	SDC19175.1	SAMN04487894_10270	SAMN04487894_101562	Starch-binding associating with outer membrane.	Starch-binding associating with outer membrane.	0.647
SDC33446.1	SDC50378.1	SAMN04487894_10270	SAMN04487894_102552	Starch-binding associating with outer membrane.	Carbohydrate binding domain-containing protein.	0.706
SDC33446.1	SDE10666.1	SAMN04487894_10270	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.763
SDC50378.1	SDC33446.1	SAMN04487894_102552	SAMN04487894_10270	Carbohydrate binding domain-containing protein.	Starch-binding associating with outer membrane.	0.706
SDC50378.1	SDE10666.1	SAMN04487894_102552	SAMN04487894_12140	Carbohydrate binding domain-containing protein.	TonB-linked outer membrane protein, SusC/RagA family.	0.755
SDC59337.1	SDE10666.1	SAMN04487894_10349	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.748
SDC99404.1	SDE10666.1	SAMN04487894_105139	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.772
SDD25735.1	SDE10666.1	SAMN04487894_107143	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.773
SDD34295.1	SDE10666.1	SAMN04487894_10887	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.767
SDE06192.1	SDE10666.1	SAMN04487894_11969	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.768
SDE10641.1	SDE10666.1	SAMN04487894_12139	SAMN04487894_12140	Starch-binding associating with outer membrane.	TonB-linked outer membrane protein, SusC/RagA family.	0.933
SDE10666.1	SDC19175.1	SAMN04487894_12140	SAMN04487894_101562	TonB-linked outer membrane protein, SusC/RagA family.	Starch-binding associating with outer membrane.	0.757
SDE10666.1	SDC19635.1	SAMN04487894_12140	SAMN04487894_101574	TonB-linked outer membrane protein, SusC/RagA family.	Starch-binding associating with outer membrane.	0.766
SDE10666.1	SDC33446.1	SAMN04487894_12140	SAMN04487894_10270	TonB-linked outer membrane protein, SusC/RagA family.	Starch-binding associating with outer membrane.	0.763
SDE10666.1	SDC50378.1	SAMN04487894_12140	SAMN04487894_102552	TonB-linked outer membrane protein, SusC/RagA family.	Carbohydrate binding domain-containing protein.	0.755
SDE10666.1	SDC59337.1	SAMN04487894_12140	SAMN04487894_10349	TonB-linked outer membrane protein, SusC/RagA family.	Starch-binding associating with outer membrane.	0.748
SDE10666.1	SDC99404.1	SAMN04487894_12140	SAMN04487894_105139	TonB-linked outer membrane protein, SusC/RagA family.	Starch-binding associating with outer membrane.	0.772

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Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

96

PPI enrichment p-value:

0.692

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006633

Fatty acid biosynthetic process

4 of 44

1.68

1.39

0.0010

GO:0006631

Fatty acid metabolic process

5 of 86

1.49

1.34

0.00057

GO:0044249

Cellular biosynthetic process

8 of 908

0.67

0.45

0.0120

GO:1901576

Organic substance biosynthetic process

8 of 950

0.65

0.44

0.0120

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004312

Fatty acid synthase activity

4 of 19

2.05

2.11

5.52e-05

GO:0004314

[Acyl-carrier-protein] S-malonyltransferase activity

2 of 2

2.72

1.14

0.0085

GO:0031177

Phosphopantetheine binding

2 of 5

2.32

1.07

0.0104

GO:0004315

3-oxoacyl-[acyl-carrier-protein] synthase activity

2 of 14

1.88

0.76

0.0352

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:451

Phosphopantetheine, and Condensation domain

8 of 21

2.3

6.37

9.28e-15

CL:454

Phosphopantetheine, and Siderophore metabolic process

7 of 14

2.42

6.17

1.56e-13

CL:456

Phosphopantetheine attachment site

6 of 7

2.65

6.03

1.88e-12

CL:434

Mixed, incl. Fatty acid biosynthetic process, and AMP-binding enzyme

11 of 99

1.77

4.72

8.59e-17

CL:435

Mixed, incl. AMP-binding enzyme, and Alpha/beta hydrolase fold-1

9 of 68

1.84

4.5

1.07e-13

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01053

Biosynthesis of siderophore group nonribosomal peptides

2 of 7

2.18

0.96

0.0160

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0596

Phosphopantetheine

6 of 18

2.24

4.52

2.85e-10

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00550

Phosphopantetheine attachment site

6 of 16

2.3

4.48

5.49e-10

PF00668

Condensation domain

4 of 10

2.32

2.84

2.96e-06

PF00698

Acyl transferase domain

3 of 3

2.72

2.46

2.88e-05

PF00501

AMP-binding enzyme

4 of 26

1.91

2.08

3.99e-05

PF13193

AMP-binding enzyme C-terminal domain

3 of 16

1.99

1.56

0.00083

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR036736

ACP-like superfamily

6 of 18

2.24

4.14

2.50e-09

IPR009081

Phosphopantetheine binding ACP domain

6 of 18

2.24

4.14

2.50e-09

IPR020806

Polyketide synthase, phosphopantetheine-binding domain

5 of 11

2.38

3.83

2.63e-08

IPR001242

Condensation domain

4 of 10

2.32

2.79

3.74e-06

IPR006162

Phosphopantetheine attachment site

4 of 12

2.24

2.68

5.43e-06

(more ...)

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