SDE21607.1 protein (Niabella drilacis) - STRING interaction network

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second shell of interactors

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

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Score

SDE21607.1

F5/8 type C domain-containing protein. (673 aa)

Predicted Functional Partners:

SDE21672.1

0.824

SDE21639.1

0.823

SDE21581.1

0.754

SDE21725.1

0.727

SDE21835.1

0.720

SDE21863.1

0.711

SDD12706.1

0.704

SDD12775.1

0.691

SDE21756.1

0.657

SDD12676.1

0.620

Your Current Organism:

Niabella drilacis

NCBI taxonomy Id: 1285928
Other names: CCM 8410, DSM 25811, LMG 26954, LMG:26954, N. drilacis, Niabella drilacis Glaeser et al. 2013, Niabella sp. E90, strain E90

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
SDD12676.1	SDD12706.1	SAMN04487894_106121	SAMN04487894_106122	N-acetylneuraminate lyase; Belongs to the DapA family.	Sialidase-1.	0.937
SDD12676.1	SDD12775.1	SAMN04487894_106121	SAMN04487894_106124	N-acetylneuraminate lyase; Belongs to the DapA family.	Sialidase-1.	0.906
SDD12676.1	SDE21607.1	SAMN04487894_106121	SAMN04487894_1274	N-acetylneuraminate lyase; Belongs to the DapA family.	F5/8 type C domain-containing protein.	0.620
SDD12706.1	SDD12676.1	SAMN04487894_106122	SAMN04487894_106121	Sialidase-1.	N-acetylneuraminate lyase; Belongs to the DapA family.	0.937
SDD12706.1	SDD12775.1	SAMN04487894_106122	SAMN04487894_106124	Sialidase-1.	Sialidase-1.	0.882
SDD12706.1	SDE21607.1	SAMN04487894_106122	SAMN04487894_1274	Sialidase-1.	F5/8 type C domain-containing protein.	0.704
SDD12775.1	SDD12676.1	SAMN04487894_106124	SAMN04487894_106121	Sialidase-1.	N-acetylneuraminate lyase; Belongs to the DapA family.	0.906
SDD12775.1	SDD12706.1	SAMN04487894_106124	SAMN04487894_106122	Sialidase-1.	Sialidase-1.	0.882
SDD12775.1	SDE21607.1	SAMN04487894_106124	SAMN04487894_1274	Sialidase-1.	F5/8 type C domain-containing protein.	0.691
SDE21581.1	SDE21607.1	SAMN04487894_1273	SAMN04487894_1274	Concanavalin A-like lectin/glucanases superfamily protein.	F5/8 type C domain-containing protein.	0.754
SDE21581.1	SDE21639.1	SAMN04487894_1273	SAMN04487894_1275	Concanavalin A-like lectin/glucanases superfamily protein.	Type I phosphodiesterase / nucleotide pyrophosphatase.	0.688
SDE21581.1	SDE21672.1	SAMN04487894_1273	SAMN04487894_1276	Concanavalin A-like lectin/glucanases superfamily protein.	Protein of unknown function.	0.863
SDE21581.1	SDE21725.1	SAMN04487894_1273	SAMN04487894_1278	Concanavalin A-like lectin/glucanases superfamily protein.	Starch-binding associating with outer membrane.	0.836
SDE21581.1	SDE21756.1	SAMN04487894_1273	SAMN04487894_1279	Concanavalin A-like lectin/glucanases superfamily protein.	TonB-linked outer membrane protein, SusC/RagA family.	0.828
SDE21581.1	SDE21835.1	SAMN04487894_1273	SAMN04487894_12712	Concanavalin A-like lectin/glucanases superfamily protein.	Starch-binding associating with outer membrane.	0.833
SDE21581.1	SDE21863.1	SAMN04487894_1273	SAMN04487894_12713	Concanavalin A-like lectin/glucanases superfamily protein.	TonB-linked outer membrane protein, SusC/RagA family.	0.835
SDE21607.1	SDD12676.1	SAMN04487894_1274	SAMN04487894_106121	F5/8 type C domain-containing protein.	N-acetylneuraminate lyase; Belongs to the DapA family.	0.620
SDE21607.1	SDD12706.1	SAMN04487894_1274	SAMN04487894_106122	F5/8 type C domain-containing protein.	Sialidase-1.	0.704
SDE21607.1	SDD12775.1	SAMN04487894_1274	SAMN04487894_106124	F5/8 type C domain-containing protein.	Sialidase-1.	0.691
SDE21607.1	SDE21581.1	SAMN04487894_1274	SAMN04487894_1273	F5/8 type C domain-containing protein.	Concanavalin A-like lectin/glucanases superfamily protein.	0.754

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Network Stats

number of nodes:

11

number of edges:

43

average node degree:

7.82

avg. local clustering coefficient:

0.921

expected number of edges:

11

PPI enrichment p-value:

2.22e-13

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000105

Histidine biosynthetic process

9 of 10

2.54

8.31

4.76e-18

GO:1901576

Organic substance biosynthetic process

11 of 722

0.77

0.78

5.44e-07

GO:0044249

Cellular biosynthetic process

10 of 679

0.76

0.72

9.24e-06

GO:0006807

Nitrogen compound metabolic process

10 of 1167

0.52

0.42

0.0013

GO:0044238

Primary metabolic process

11 of 1510

0.45

0.37

0.00086

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016763

Pentosyltransferase activity

3 of 14

1.92

1.15

0.0056

GO:0004424

Imidazoleglycerol-phosphate dehydratase activity

2 of 2

2.59

1.06

0.0119

GO:0004401

Histidinol-phosphatase activity

2 of 2

2.59

1.06

0.0119

GO:0000107

Imidazoleglycerol-phosphate synthase activity

2 of 2

2.59

1.06

0.0119

GO:0016829

Lyase activity

4 of 127

1.09

0.6

0.0312

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

11 of 1192

0.55

0.48

0.00010

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:933

Histidine biosynthesis

8 of 8

2.59

7.48

7.58e-16

CL:889

Phenylalanine, tyrosine and tryptophan biosynthesis, and Histidine biosynthetic process

9 of 32

2.04

5.53

7.20e-15

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00340

Histidine metabolism

9 of 28

2.09

6.05

6.56e-16

map01230

Biosynthesis of amino acids

9 of 139

1.4

2.39

1.84e-10

map01110

Biosynthesis of secondary metabolites

9 of 507

0.84

0.83

9.44e-06

map01100

Metabolic pathways

10 of 1519

0.41

0.32

0.0079

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005622

Intracellular

10 of 1333

0.46

0.32

0.0218

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0368

Histidine biosynthesis

8 of 9

2.54

7.55

3.03e-16

KW-0963

Cytoplasm

8 of 218

1.15

1.43

5.40e-07

KW-0456

Lyase

3 of 65

1.25

0.66

0.0299

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