STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (237 aa)    
Predicted Functional Partners:
queC
7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)).
 
 
 0.999
queD
6-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.999
queF
7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily.
 
  
 0.981
nrdD
Anaerobic ribonucleoside triphosphate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.854
AMG96781.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.726
AMG96782.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.640
AMG96776.1
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.638
AMG96775.1
Aminodeoxychorismate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.635
AMG96777.1
Aminobenzoate synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.635
kipI_2
Allophanate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
Your Current Organism:
Staphylococcus simulans
NCBI taxonomy Id: 1286
Other names: ATCC 27848, CCUG 7327 A, CIP 81.64, DSM 20322, HAMBI 2058, JCM 2424, NCTC 11046, NRRL B-14753, S. simulans
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