node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
UCREL1_10334 | UCREL1_11593 | M7SEV5 | M7SV62 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.966 |
UCREL1_10334 | UCREL1_3787 | M7SEV5 | M7SRT7 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Putative amp deaminase protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.973 |
UCREL1_10334 | UCREL1_3955 | M7SEV5 | M7SRC1 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.717 |
UCREL1_10334 | UCREL1_605 | M7SEV5 | M7T6R6 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Putative bifunctional purine biosynthesis protein. | 0.994 |
UCREL1_10334 | UCREL1_6069 | M7SEV5 | M7SRR2 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Putative carbamoyl-phosphate synthase protein. | 0.463 |
UCREL1_10334 | UCREL1_6286 | M7SEV5 | M7TJ50 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Putative asparagine synthetase protein. | 0.501 |
UCREL1_10334 | UCREL1_9347 | M7SEV5 | M7SBX8 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.974 |
UCREL1_11593 | UCREL1_10334 | M7SV62 | M7SEV5 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.966 |
UCREL1_11593 | UCREL1_3787 | M7SV62 | M7SRT7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative amp deaminase protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.927 |
UCREL1_11593 | UCREL1_605 | M7SV62 | M7T6R6 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative bifunctional purine biosynthesis protein. | 0.944 |
UCREL1_11593 | UCREL1_9347 | M7SV62 | M7SBX8 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.940 |
UCREL1_3343 | UCREL1_5696 | M7TI72 | M7SS27 | Aspartate aminotransferase. | Putative argininosuccinate synthase protein. | 0.922 |
UCREL1_3343 | UCREL1_6069 | M7TI72 | M7SRR2 | Aspartate aminotransferase. | Putative carbamoyl-phosphate synthase protein. | 0.915 |
UCREL1_3343 | UCREL1_6286 | M7TI72 | M7TJ50 | Aspartate aminotransferase. | Putative asparagine synthetase protein. | 0.971 |
UCREL1_3343 | UCREL1_7874 | M7TI72 | M7T5T0 | Aspartate aminotransferase. | Aspartate aminotransferase. | 0.960 |
UCREL1_3343 | UCREL1_9347 | M7TI72 | M7SBX8 | Aspartate aminotransferase. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.915 |
UCREL1_3787 | UCREL1_10334 | M7SRT7 | M7SEV5 | Putative amp deaminase protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.973 |
UCREL1_3787 | UCREL1_11593 | M7SRT7 | M7SV62 | Putative amp deaminase protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.927 |
UCREL1_3787 | UCREL1_3955 | M7SRT7 | M7SRC1 | Putative amp deaminase protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.940 |
UCREL1_3787 | UCREL1_605 | M7SRT7 | M7T6R6 | Putative amp deaminase protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | Putative bifunctional purine biosynthesis protein. | 0.925 |