node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
UCREL1_11536 | UCREL1_1813 | M7SBK2 | M7SX28 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative ubiquitin-like modifier protein. | 0.864 |
UCREL1_11536 | UCREL1_6058 | M7SBK2 | M7SR10 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.969 |
UCREL1_11536 | UCREL1_6285 | M7SBK2 | M7SQH0 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative sumo-conjugating enzyme ubc9 protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.837 |
UCREL1_11536 | UCREL1_9785 | M7SBK2 | M7SGJ5 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | Putative dna repair protein. | 0.550 |
UCREL1_1813 | UCREL1_11536 | M7SX28 | M7SBK2 | Putative ubiquitin-like modifier protein. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] | 0.864 |
UCREL1_1813 | UCREL1_6058 | M7SX28 | M7SR10 | Putative ubiquitin-like modifier protein. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.906 |
UCREL1_1813 | UCREL1_6151 | M7SX28 | M7SRJ0 | Putative ubiquitin-like modifier protein. | Putative condensin subunit protein. | 0.523 |
UCREL1_1813 | UCREL1_6285 | M7SX28 | M7SQH0 | Putative ubiquitin-like modifier protein. | Putative sumo-conjugating enzyme ubc9 protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.999 |
UCREL1_1813 | UCREL1_7905 | M7SX28 | M7TEL8 | Putative ubiquitin-like modifier protein. | Structural maintenance of chromosomes protein. | 0.523 |
UCREL1_1813 | UCREL1_9718 | M7SX28 | M7SAU8 | Putative ubiquitin-like modifier protein. | Putative ubiquitin-conjugating enzyme protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.607 |
UCREL1_1813 | UCREL1_9785 | M7SX28 | M7SGJ5 | Putative ubiquitin-like modifier protein. | Putative dna repair protein. | 0.874 |
UCREL1_2597 | UCREL1_3522 | M7T0K9 | M7SSH1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Putative thymidylate synthase protein. | 0.946 |
UCREL1_2597 | UCREL1_6058 | M7T0K9 | M7SR10 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.759 |
UCREL1_2597 | UCREL1_6151 | M7T0K9 | M7SRJ0 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Putative condensin subunit protein. | 0.512 |
UCREL1_2597 | UCREL1_7905 | M7T0K9 | M7TEL8 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Structural maintenance of chromosomes protein. | 0.483 |
UCREL1_3522 | UCREL1_2597 | M7SSH1 | M7T0K9 | Putative thymidylate synthase protein. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.946 |
UCREL1_3522 | UCREL1_6058 | M7SSH1 | M7SR10 | Putative thymidylate synthase protein. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.782 |
UCREL1_3522 | UCREL1_6151 | M7SSH1 | M7SRJ0 | Putative thymidylate synthase protein. | Putative condensin subunit protein. | 0.423 |
UCREL1_3522 | UCREL1_9718 | M7SSH1 | M7SAU8 | Putative thymidylate synthase protein. | Putative ubiquitin-conjugating enzyme protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.487 |
UCREL1_5723 | UCREL1_6058 | M7TBL2 | M7SR10 | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. | 0.815 |