UCREL1_6877 protein (Eutypa lata) - STRING interaction network

Nodes:

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

UCREL1_6877

Putative taurine catabolism dioxygenase protein. (393 aa)

Predicted Functional Partners:

UCREL1_11817

0.621

UCREL1_8564

0.610

UCREL1_8565

0.610

UCREL1_4490

0.610

UCREL1_9879

0.606

UCREL1_6670

0.583

UCREL1_11154

0.557

UCREL1_2335

0.557

UCREL1_6512

0.540

UCREL1_11787

0.534

Your Current Organism:

Eutypa lata

NCBI taxonomy Id: 1287681
Other names: E. lata UCREL1, Eutypa lata UCREL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
UCREL1_11154	UCREL1_11817	M7SWG2	M7SAS9	Putative heat shock protein 70-like protein.	Putative glucose-regulated protein; Belongs to the heat shock protein 70 family.	0.940
UCREL1_11154	UCREL1_2335	M7SWG2	M7T1C9	Putative heat shock protein 70-like protein.	Putative heat shock protein 70-like protein.	0.865
UCREL1_11154	UCREL1_4490	M7SWG2	M7TEY6	Putative heat shock protein 70-like protein.	Putative tuberous sclerosis 1 protein.	0.672
UCREL1_11154	UCREL1_6512	M7SWG2	M7SQL1	Putative heat shock protein 70-like protein.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.694
UCREL1_11154	UCREL1_6670	M7SWG2	M7SPF9	Putative heat shock protein 70-like protein.	Putative hsp70-like protein; Belongs to the heat shock protein 70 family.	0.418
UCREL1_11154	UCREL1_6877	M7SWG2	M7T8L1	Putative heat shock protein 70-like protein.	Putative taurine catabolism dioxygenase protein.	0.557
UCREL1_11154	UCREL1_8564	M7SWG2	M7T3R0	Putative heat shock protein 70-like protein.	Putative flavin reductase like domain-containing protein.	0.672
UCREL1_11154	UCREL1_8565	M7SWG2	M7TCS3	Putative heat shock protein 70-like protein.	Putative heat shock protein 90 protein.	0.672
UCREL1_11787	UCREL1_11817	M7SAV1	M7SAS9	Putative hsp70 protein.	Putative glucose-regulated protein; Belongs to the heat shock protein 70 family.	0.578
UCREL1_11787	UCREL1_4490	M7SAV1	M7TEY6	Putative hsp70 protein.	Putative tuberous sclerosis 1 protein.	0.680
UCREL1_11787	UCREL1_6512	M7SAV1	M7SQL1	Putative hsp70 protein.	GrpE protein homolog; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the GrpE family.	0.694
UCREL1_11787	UCREL1_6670	M7SAV1	M7SPF9	Putative hsp70 protein.	Putative hsp70-like protein; Belongs to the heat shock protein 70 family.	0.462
UCREL1_11787	UCREL1_6877	M7SAV1	M7T8L1	Putative hsp70 protein.	Putative taurine catabolism dioxygenase protein.	0.534
UCREL1_11787	UCREL1_8564	M7SAV1	M7T3R0	Putative hsp70 protein.	Putative flavin reductase like domain-containing protein.	0.680
UCREL1_11787	UCREL1_8565	M7SAV1	M7TCS3	Putative hsp70 protein.	Putative heat shock protein 90 protein.	0.680
UCREL1_11787	UCREL1_9879	M7SAV1	M7SAJ9	Putative hsp70 protein.	Putative heat shock protein hsp88 protein.	0.584
UCREL1_11817	UCREL1_11154	M7SAS9	M7SWG2	Putative glucose-regulated protein; Belongs to the heat shock protein 70 family.	Putative heat shock protein 70-like protein.	0.940
UCREL1_11817	UCREL1_11787	M7SAS9	M7SAV1	Putative glucose-regulated protein; Belongs to the heat shock protein 70 family.	Putative hsp70 protein.	0.578
UCREL1_11817	UCREL1_2335	M7SAS9	M7T1C9	Putative glucose-regulated protein; Belongs to the heat shock protein 70 family.	Putative heat shock protein 70-like protein.	0.928
UCREL1_11817	UCREL1_4490	M7SAS9	M7TEY6	Putative glucose-regulated protein; Belongs to the heat shock protein 70 family.	Putative tuberous sclerosis 1 protein.	0.730

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.883

expected number of edges:

11

PPI enrichment p-value:

4.81e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0042953

Lipoprotein transport

4 of 12

2.17

2.26

3.51e-05

GO:0045184

Establishment of protein localization

6 of 113

1.37

1.54

3.56e-05

GO:0015031

Protein transport

5 of 102

1.34

1.28

0.00033

GO:0072657

Protein localization to membrane

3 of 24

1.75

1.22

0.0031

GO:0071705

Nitrogen compound transport

6 of 204

1.12

1.04

0.00035

(more ...)

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:26500826

(2015) Anvio: an advanced analysis and visualization platform for omics data.

4 of 6

2.47

3.3

4.85e-07

PMID:29737840

(2018) Tyr51: Key Determinant of the Low Thermostability of the Colwellia psychrerythraea Cold-Shock Protein.

3 of 4

2.52

2.46

2.49e-05

PMID:23536799

(2013) Amino acid substitutions in cold-adapted proteins from Halorubrum lacusprofundi, an extremely halophilic microbe from antarctica.

3 of 4

2.52

2.46

2.49e-05

PMID:25975821

(2015) Microarray transcriptional profiling of Arctic Mesorhizobium strain N33 at low temperature provides insights into cold adaption strategies.

3 of 8

2.22

2.18

5.84e-05

PMID:24278781

(2013) Psychrophilic enzymes: from folding to function and biotechnology.

3 of 10

2.13

2.08

8.08e-05

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1378

Mixed, incl. Outer membrane protein, bacterial, and Bacteriocin transport

6 of 14

2.28

4.36

9.51e-10

CL:1380

Mixed, incl. Bacteriocin transport, and Outer membrane lipoprotein

3 of 7

2.28

1.89

0.00026

CL:2671

Mixed, incl. Cold shock, CspA, and Histone-like DNA-binding protein

3 of 20

1.83

1.25

0.0030

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0098796

Membrane protein complex

5 of 140

1.2

0.94

0.0026

GOCC:0098797

Plasma membrane protein complex

3 of 39

1.54

0.88

0.0142

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0132

Cell division

3 of 37

1.56

0.84

0.0182

KW-0131

Cell cycle

3 of 37

1.56

0.84

0.0182

KW-0449

Lipoprotein

4 of 125

1.15

0.69

0.0182

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR019844

Cold-shock (CSD) domain

3 of 3

2.65

1.92

0.00030

IPR012156

Cold shock, CspA

3 of 4

2.52

1.9

0.00030

IPR002059

Cold-shock protein, DNA-binding

3 of 5

2.43

1.88

0.00030

IPR011129

Cold shock domain

3 of 7

2.28

1.77

0.00045

IPR011925

Lipoprotein-releasing system transmembrane protein LolC/E

2 of 2

2.65

1.1

0.0099

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00357

Cold shock protein domain

3 of 7

2.28

2.02

0.00014

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