STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCQ72814.1Putative Adenylate cyclase, contains HAMP domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (597 aa)    
Predicted Functional Partners:
ndk
Nucleoside diphosphate kinase (NDK) (NDP kinase) (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.901
pyk
Pyruvate kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the pyruvate kinase family.
    
 0.901
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
     
  0.900
CCQ73791.1
Protein mazG, nucleoside triphosphate pyrophosphohydrolase; Function of strongly homologous gene; enzyme.
     
  0.900
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.
   
  0.804
folE
GTP cyclohydrolase I; Function of strongly homologous gene; enzyme.
     
  0.800
CCQ73688.1
Protein of unknown function.Containing adenylate cyclase domain; No homology to any previously reported sequences.
  
     0.775
cpdA
Putative metallophosphoesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.723
CCQ75193.1
Putative metallophosphoesterase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
  
 0.720
CCQ73753.1
Protein of unknown function. Containing cAMP-binding domain; No homology to any previously reported sequences.
  
 
   0.709
Your Current Organism:
Magnetospira sp. QH2
NCBI taxonomy Id: 1288970
Other names: M. sp. QH-2, Magnetospira sp. QH-2, marine magnetic spirillum QH-2
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.