node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCQ72949.1 | CCQ75423.1 | MGMAQ_1002 | MGMAQ_3611 | Putative non ribosomal peptide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.566 |
CCQ72949.1 | ubiA | MGMAQ_1002 | MGMAQ_2878 | Putative non ribosomal peptide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative 4-hydroxybenzoate-octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.582 |
CCQ72949.1 | ubiE | MGMAQ_1002 | MGMAQ_1208 | Putative non ribosomal peptide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.479 |
CCQ72949.1 | ubiE-2 | MGMAQ_1002 | MGMAQ_3937 | Putative non ribosomal peptide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.479 |
CCQ73141.1 | CCQ73142.1 | MGMAQ_1210 | MGMAQ_1211 | Homologs of previously reported genes of unknown function. | Putative cyclase/dehydrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.768 |
CCQ73141.1 | menA | MGMAQ_1210 | MGMAQ_1209 | Homologs of previously reported genes of unknown function. | 1,4-Dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.632 |
CCQ73141.1 | ubiE | MGMAQ_1210 | MGMAQ_1208 | Homologs of previously reported genes of unknown function. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.548 |
CCQ73142.1 | CCQ73141.1 | MGMAQ_1211 | MGMAQ_1210 | Putative cyclase/dehydrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Homologs of previously reported genes of unknown function. | 0.768 |
CCQ73142.1 | menA | MGMAQ_1211 | MGMAQ_1209 | Putative cyclase/dehydrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 1,4-Dihydroxy-2-naphtoate prenyltransferase; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. | 0.537 |
CCQ73142.1 | ubiE | MGMAQ_1211 | MGMAQ_1208 | Putative cyclase/dehydrase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.537 |
CCQ75423.1 | CCQ72949.1 | MGMAQ_3611 | MGMAQ_1002 | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative non ribosomal peptide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.566 |
CCQ75423.1 | coq7 | MGMAQ_3611 | MGMAQ_3634 | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Ubiquinone biosynthesis protein COQ7 homolog; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | 0.895 |
CCQ75423.1 | ubiA | MGMAQ_3611 | MGMAQ_2878 | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative 4-hydroxybenzoate-octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.717 |
CCQ75423.1 | ubiD | MGMAQ_3611 | MGMAQ_2783 | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UbiD family. | 0.413 |
CCQ75423.1 | ubiE | MGMAQ_3611 | MGMAQ_1208 | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.924 |
CCQ75423.1 | ubiE-2 | MGMAQ_3611 | MGMAQ_3937 | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.939 |
coq7 | CCQ75423.1 | MGMAQ_3634 | MGMAQ_3611 | Putative Ubiquinone biosynthesis protein COQ7 homolog; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Putative 2-polyprenyl-6-methoxyphenol 4-hydroxylase[Include FAD dependent oxidoreductase domain]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.895 |
coq7 | ubiA | MGMAQ_3634 | MGMAQ_2878 | Putative Ubiquinone biosynthesis protein COQ7 homolog; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Putative 4-hydroxybenzoate-octaprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.581 |
coq7 | ubiE | MGMAQ_3634 | MGMAQ_1208 | Putative Ubiquinone biosynthesis protein COQ7 homolog; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.907 |
coq7 | ubiE-2 | MGMAQ_3634 | MGMAQ_3937 | Putative Ubiquinone biosynthesis protein COQ7 homolog; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. | Ubiquinone/menaquinone biosynthesis methyltransferase ubiE; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). | 0.920 |