STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folP7,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (273 aa)    
Predicted Functional Partners:
CCQ73569.1
2-amino-4-hydroxy-6- hydroxymethyldihydropteridinepyrophosphokinase; Function of strongly homologous gene; enzyme.
 
 
 0.998
CCQ72593.1
Folylpolyglutamate synthase; Function of strongly homologous gene; enzyme; Belongs to the folylpolyglutamate synthase family.
 
 0.997
CCQ74860.1
Putative dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.995
folE
GTP cyclohydrolase I; Function of strongly homologous gene; enzyme.
  
 0.987
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
  
 0.921
ftsH
Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
  
  
 0.828
guaB
Inosine-5'-monophosphate dehydrogenase (IMP dehydrogenase) (IMPDH) (IMPD); Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
  
 0.800
CCQ73324.1
Phosphomethylpyrimidine kinase; Function of strongly homologous gene; enzyme.
     
 0.754
etfD
Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone.
 
 
  
 0.725
ribD
Bifunctional: diaminohydroxyphosphoribosylaminopyrimidine deaminase (N-terminal); Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
     
 0.619
Your Current Organism:
Magnetospira sp. QH2
NCBI taxonomy Id: 1288970
Other names: M. sp. QH-2, Magnetospira sp. QH-2, marine magnetic spirillum QH-2
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.