STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnAGlutamine synthetase I (Glutamate--ammonia ligase I) (GSI); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (473 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.988
glmS
L-glutamine:D-fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.944
gltD
Glutamate synthase, small subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.936
carB
Carbamoyl phosphate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarB family.
  
 
 0.935
carA
Carbamoyl-phosphate synthase (glutamine-hydrolysing); Function of strongly homologous gene; enzyme; Belongs to the CarA family.
  
 
 0.932
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine.
    
 0.925
gdh
NAD-glutamate dehydrogenase; Function of strongly homologous gene; enzyme.
     
 0.920
amiF
Formamidase (Formamide amidohydrolase); Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide; Belongs to the carbon-nitrogen hydrolase superfamily. Aliphatic amidase family.
    
 0.916
purQ
Phosphoribosylformylglycinamidine synthase, purQ subunit; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...]
    
 0.912
glnB-2
Nitrogen regulatory protein P-II; Function of homologous gene experimentally demonstrated in an other organism; regulator; Belongs to the P(II) protein family.
  
  
 0.885
Your Current Organism:
Magnetospira sp. QH2
NCBI taxonomy Id: 1288970
Other names: M. sp. QH-2, Magnetospira sp. QH-2, marine magnetic spirillum QH-2
Server load: low (22%) [HD]