STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCQ75375.1Putative uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (241 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.997
CCQ75374.1
Protein of unknown function; No homology to any previously reported sequences.
     0.962
CCQ75373.1
Conserved protein of unknown function[Include HemY protein N-terminal domain]; Homologs of previously reported genes of unknown function.
 
     0.949
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.947
cobA
Uroporphyrinogen-III methylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.
  
 
 0.938
hemB
Delta-aminolevulinic acid dehydratase (porphobilinogen synthase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family.
  
 
 0.875
CCQ75371.1
Putative xylanase/chitin deacetylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.773
CCQ75372.1
Homologs of previously reported genes of unknown function.
       0.773
tsaD
Putative O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
  
 0.745
CCQ72046.1
Putative potassium channel protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
    0.680
Your Current Organism:
Magnetospira sp. QH2
NCBI taxonomy Id: 1288970
Other names: M. sp. QH-2, Magnetospira sp. QH-2, marine magnetic spirillum QH-2
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