STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM56268.1Signal transduction diguanylate cyclase. (612 aa)    
Predicted Functional Partners:
luxS
S-ribosylhomocysteinase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5-dihydroxy-2,3-pentadione (DPD). Belongs to the LuxS family.
       0.491
KRM55442.1
Diguanylate cyclase phosphodiesterase domain-containing protein.
 
  
0.484
KRM56101.1
Glycosyltransferase.
 
 
 0.483
KRM55130.1
Hypothetical protein.
 
  
0.458
KRM56306.1
Hypothetical protein.
 
   
0.437
KRM55216.1
Hypothetical protein.
 
   
0.436
KRM55161.1
Hypothetical protein.
 
  
0.436
KRM55512.1
Diguanylate cyclase phosphodiesterase domain-containing protein.
 
   
0.434
KRM56304.1
Diguanylate cyclase phosphodiesterase domain-containing protein.
 
   
0.433
KRM56305.1
Diguanylate cyclase phosphodiesterase domain-containing protein.
 
   
0.428
Your Current Organism:
Lactobacillus sharpeae
NCBI taxonomy Id: 1291052
Other names: L. sharpeae JCM 1186 = DSM 20505, Lactobacillus sharpeae DSM 20505, Lactobacillus sharpeae JCM 1186 = DSM 20505, Lactobacillus sharpeae LMG 9214, Lactobacillus sharpeae NCIB 11720
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