node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRM55413.1 | KRM55665.1 | FC18_GL001308 | FC18_GL001171 | Rna polymerase sigma-54 factor rpon. | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | 0.482 |
KRM55413.1 | topA | FC18_GL001308 | FC18_GL000789 | Rna polymerase sigma-54 factor rpon. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.575 |
KRM55665.1 | KRM55413.1 | FC18_GL001171 | FC18_GL001308 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | Rna polymerase sigma-54 factor rpon. | 0.482 |
KRM55665.1 | KRM55666.1 | FC18_GL001171 | FC18_GL001172 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | ABC superfamily ATP binding cassette transporter, ABC protein. | 0.503 |
KRM55665.1 | KRM55699.1 | FC18_GL001171 | FC18_GL001072 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | Membrane-associated Zn-dependent protease 1. | 0.598 |
KRM55665.1 | atpE | FC18_GL001171 | FC18_GL002009 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | Hypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | 0.535 |
KRM55665.1 | lepA | FC18_GL001171 | FC18_GL000318 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | GTP-binding translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.633 |
KRM55665.1 | lepA-2 | FC18_GL001171 | FC18_GL001095 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.675 |
KRM55665.1 | lspA | FC18_GL001171 | FC18_GL000815 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.532 |
KRM55665.1 | rnc | FC18_GL001171 | FC18_GL000017 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.459 |
KRM55665.1 | rnhB | FC18_GL001171 | FC18_GL000787 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.640 |
KRM55665.1 | topA | FC18_GL001171 | FC18_GL000789 | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.550 |
KRM55666.1 | KRM55665.1 | FC18_GL001172 | FC18_GL001171 | ABC superfamily ATP binding cassette transporter, ABC protein. | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | 0.503 |
KRM55699.1 | KRM55665.1 | FC18_GL001072 | FC18_GL001171 | Membrane-associated Zn-dependent protease 1. | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | 0.598 |
KRM55699.1 | topA | FC18_GL001072 | FC18_GL000789 | Membrane-associated Zn-dependent protease 1. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.612 |
atpE | KRM55665.1 | FC18_GL002009 | FC18_GL001171 | Hypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | 0.535 |
lepA | KRM55665.1 | FC18_GL000318 | FC18_GL001171 | GTP-binding translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | 0.633 |
lepA | topA | FC18_GL000318 | FC18_GL000789 | GTP-binding translation elongation factor LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.520 |
lepA-2 | KRM55665.1 | FC18_GL001095 | FC18_GL001171 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Type I signal peptidase-like protein; Belongs to the peptidase S26 family. | 0.675 |
lepA-2 | topA | FC18_GL001095 | FC18_GL000789 | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.520 |