STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRM55487.1HD superfamily hydrolase. (216 aa)    
Predicted Functional Partners:
KRM55486.1
Oxidoreductase.
       0.765
KRM55488.1
Hypothetical protein.
       0.648
KRM55489.1
Hypothetical protein.
       0.648
KRM55485.1
Hypothetical protein.
       0.549
KRM56179.1
Deoxyguanosine kinase.
 
     0.469
cinA
Competence-damage inducible protein; Belongs to the CinA family.
  
 
  0.452
KRM56090.1
Guanosine polyphosphate pyrophosphohydrolase synthetase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
   
 
 0.434
nadK
Inorganic polyphosphate ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
  
  0.428
cca
tRNA nucleotidyltransferase poly(A) polymerase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate.
  
 
 0.413
KRM55499.1
Deoxyguanosine kinase.
 
     0.407
Your Current Organism:
Lactobacillus sharpeae
NCBI taxonomy Id: 1291052
Other names: L. sharpeae JCM 1186 = DSM 20505, Lactobacillus sharpeae DSM 20505, Lactobacillus sharpeae JCM 1186 = DSM 20505, Lactobacillus sharpeae LMG 9214, Lactobacillus sharpeae NCIB 11720
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.