STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mrnCRibonuclease III; Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc); Rnc processes 30S rRNA into smaller rRNA precursors; Belongs to the MrnC RNase family. (139 aa)    
Predicted Functional Partners:
cysS
cysteinyl-tRNA synthetase; Anticodon-binding domain of cysteinyl tRNA synthetases; cd07963; HIGH motif; KMSKS motif; anticodon binding site; catalytic core domain of cysteinyl tRNA synthetase; cd00672; cysteinyl-tRNA synthetase [Lactobacillus rhamnosus GG]; cysteinyl-tRNA synthetase; Validated; PRK00260; gene_438; identified by MetaGeneAnnotator; putative; strain coidentity: ATCC 53103 = GG; synonym: Lactobacillus rhamnosus ATCC 53103; tRNA binding surface [nucleotide binding]; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.977
BAP85020.1
RNA 2'-O ribose methyltransferase substrate binding; pfam08032; SpoU rRNA Methylase family; pfam00588; gene_440; identified by MetaGeneAnnotator; putative; lreu_v1_TGAC_scaffold_08; rRNA methylase, putative, group 3; TIGR00186; tRNA/rRNA methyltransferase [Lactobacillus reuteri ATCC 53608]; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.
 
  
 0.926
BAP85910.1
RNA-binding protein; Gene_1330; identified by MetaGeneAnnotator; putative.
  
   
 0.745
rplC
50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
 
 0.728
gltX
glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.
     
 0.702
fbpA
Fibronectin-binding protein A; COG: COG1293; Pfam: PF05833,PF05670; InterPro: IPR008616; Domain of unknown function (DUF814); pfam05670; Fibronectin-binding protein A N-terminus (FbpA); pfam05833; fibronectin-binding protein [Lactobacillus antri DSM 16041]; gene_1059; identified by MetaGeneAnnotator; putative.
 
     0.679
polC
DNA polymerase III subunit alpha; Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
  
    0.639
BAP86039.1
UPF0297 protein [Lactobacillus fermentum 28-3-CHN]; gene_1459; hypothetical protein; Provisional; identified by MetaGeneAnnotator; putative.
  
     0.623
sepF
Cell division protein SepF; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA.
  
    0.595
BAP85586.1
DNA-binding protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.591
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.