STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAP85085.1CtsR family transcriptional regulator; COG: COG4463; Firmicute transcriptional repressor of class III stress genes (CtsR); pfam05848; gene_505; identified by MetaGeneAnnotator; putative; transcriptional regulator CtsR [Lactobacillus reuteri MM2- 3]; Belongs to the CtsR family. (155 aa)    
Predicted Functional Partners:
BAP85086.1
ATP binding site [chemical binding]; ATP-binding subunit of Clp protease and DnaK/DnaJ chaperones [Lactobacillus brevis ATCC 367]; C-terminal, D2-small domain, of ClpB protein; pfam10431; Clp amino terminal domain; pfam02861; Clp protease ATP binding subunit; CHL00095; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009; UvrB/uvrC motif; pfam02151; Walker A motif; Walker B moti [...]
  
  
 0.949
BAP85252.1
ATP-dependent Clp protease ATP-binding protein; ATP binding site [chemical binding]; ATP-binding subunit of chaperone [Lactobacillus fermentum ATCC 14931]; ATPases associated with a variety of cellular activities; smart00382; C-terminal, D2-small domain, of ClpB protein; pfam10431; The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; cd00009; UvrB/uvrC motif; pfam02151; Walker A motif; [...]
  
  
 0.649
hrcA
Heat-inducible transcriptional repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
   
  
 0.593
BAP85016.1
Twitching motility protein PilT; COG: COG4956; Integral membrane protein (PIN domain superfamily) [General function prediction only]; PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; cd09877; PilT domain protein [Lactobacillus reuteri MM2- 3]; gene_436; identified by MetaGeneAnnotator; putative; putative active site [active].
 
    0.466
BAP85586.1
DNA-binding protein; Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY/ffh. May be a regulatory protein.
  
     0.456
BAP85087.1
TetR family transcriptional regulator; Gene_507; identified by MetaGeneAnnotator; putative.
       0.450
clpP
ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
   
  
 0.434
groES
Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.433
birA
biotin--[acetyl-CoA-carboxylase] ligase and biotin operon repressor; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
      
 0.430
BAP85552.1
Alkaline shock protein; Asp23 family; pfam03780; COG: COG1302; alkaline shock protein [Lactobacillus reuteri MM2-3]; gene_972; identified by MetaGeneAnnotator; putative.
  
     0.421
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.