STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mscLLarge conductance mechanosensitive channel protein MscL; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (128 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
   
    0.660
BAP85387.1
COG: COG1052; D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; pfam02826; Lactate dehydrogenase and related dehydrogenases [Energy production and conversion / Coenzyme metabolism / General function prediction only]; COG1052; NAD+ binding site [chemical binding]; gene_807; glyoxylate reductase [Lactobacillus vaginalis ATCC 49540]; identified by MetaGeneAnnotator; putative.
       0.659
BAP84971.1
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
     
 0.576
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
     
 0.517
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.479
BAP86411.1
Potassium transporter; Gene_1831; identified by MetaGeneAnnotator; putative.
     
 0.475
cspA-2
COG1278 Cold shock proteins; Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea. CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box protein; cd04458; DNA-binding site [nucleotide binding]; RNA-binding motif; cold shock protein [Kurthia sp. JC30]; gene_1326; identified by MetaGeneAnnotator; putative; scaffold00001.
   
  
 0.468
BAP85384.1
Beta-phosphoglucomutase; Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; cd01427; KEGG: lbr:LVIS_1518 7.1e-80 HAD family sugar phosphatase; K01838 beta-phosphoglucomutase; beta-phosphoglucomutase [Lactobacillus parafarraginis F0439]; beta-phosphoglucomutase; TIGR01990; gene_804; identified by MetaGeneAnnotator; putative; motif II.
       0.465
BAP85385.1
Kojibiose phosphorylase; COG0841 Cation/multidrug efflux pump; Glycosyl hydrolase family 65 central catalytic domain; pfam03632; Glycosyl hydrolase family 65, C-terminal domain; pfam03633; Glycosyl hydrolase family 65, N-terminal domain; pfam03636; Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; COG1554; gene_805; glycosyl hydrolase [Lactobacillus coryniformis subsp. coryniformis KCTC 3167]; identified by MetaGeneAnnotator; putative.
       0.460
BAP85388.1
Hypothetical protein; Gene_808; identified by MetaGeneAnnotator; putative.
       0.459
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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