STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
miaAtRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (305 aa)    
Predicted Functional Partners:
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
  
 0.769
BAP85476.1
Protein of unknown function (DUF3042); pfam11240; gene_896; identified by MetaGeneAnnotator; putative; predicted protein [Lactobacillus coleohominis 101-4- CHN].
       0.728
glnR
Glutamine synthetase repressor; COG: COG0789; Pfam: PF00376; InterPro: IPR000551; DNA binding residues [nucleotide binding]; Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; cd01105; MerR HTH family regulatory protein; pfam13411; gene_898; glutamine synthetase repressor [Lactobacillus hilgardii ATCC 8290]; identified by MetaGeneAnnotator; putative; putative dimer interface [polypeptide binding].
       0.719
BAP85479.1
Glutamine synthetase, beta-Grasp domain; pfam03951; Glutamine synthetase, catalytic domain; pfam00120; gene_899; glutamine synthetase [Lactobacillus brevis ATCC 367]; glutamine synthetase, type I; TIGR00653; identified by MetaGeneAnnotator; putative.
       0.699
ybeY
rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
  
 0.650
pheT
phenylalanyl-tRNA synthase subunit beta; B3/4 domain; pfam03483; COG: COG0072; Ferredoxin-fold anticodon binding domain; pfam03147; Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an..; cd00769; dimer interface [polypeptide binding]; gene_883; identified by MetaGeneAnnotator; putative; motif 1; motif 2; motif 3; phenylalanyl-tRNA synthetase subunit beta [Lactobacillus vaginalis ATCC 49540]; phen [...]
 
  
 0.643
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 
  
 0.631
gatA
aspartyl/glutamyl-tRNA amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln).
 
      0.614
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
 
  
 0.609
hflX
GTP-binding protein HflX; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.
  
  
 0.597
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.