STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
BAP85479.1Glutamine synthetase, beta-Grasp domain; pfam03951; Glutamine synthetase, catalytic domain; pfam00120; gene_899; glutamine synthetase [Lactobacillus brevis ATCC 367]; glutamine synthetase, type I; TIGR00653; identified by MetaGeneAnnotator; putative. (446 aa)    
Predicted Functional Partners:
glnR
Glutamine synthetase repressor; COG: COG0789; Pfam: PF00376; InterPro: IPR000551; DNA binding residues [nucleotide binding]; Helix-Turn-Helix DNA binding domain of GlnR-like transcription regulators; cd01105; MerR HTH family regulatory protein; pfam13411; gene_898; glutamine synthetase repressor [Lactobacillus hilgardii ATCC 8290]; identified by MetaGeneAnnotator; putative; putative dimer interface [polypeptide binding].
 
 
 0.973
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
 
 
 0.964
BAP84658.1
Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; pfam02812; NAD(P) binding domain of glutamate dehydrogenase, subgroup 2; cd05313; NAD(P) binding site [chemical binding]; gene_78; glutamate dehydrogenase [Lactobacillus rhamnosus GG]; glutamate dehydrogenase; Provisional; identified by MetaGeneAnnotator; putative; strain coidentity: ATCC 53103 = GG; synonym: Lactobacillus rhamnosus ATCC 53103; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.925
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.919
carA
Carbamoyl-phosphate synthase small subunit; Gene_29; identified by MetaGeneAnnotator; putative; Belongs to the CarA family.
  
 
 0.917
carA-3
COG: COG0505; Carbamoyl-phosphate synthase small chain, CPSase domain; pfam00988; Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; cd01744; carbamoyl phosphate synthase small subunit [Lactobacillus reuteri MM2- 3]; carbamoyl phosphate synthase small subunit; Reviewed; catalytic site [active]; gene_1057; identified by MetaGeneAnnotator; putative; subunit interface [polypeptide binding]; Belongs to the CarA family.
  
 
 0.917
carA-2
Carbamoyl-phosphate synthase small chain, CPSase domain; smart01097; Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; cd01744; carbamoyl phosphate synthase small subunit [Lactobacillus plantarum JDM1]; carbamoyl phosphate synthase small subunit; Reviewed; catalytic site [active]; catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; gene_2142; identified by MetaGeneAnnotator; putative; subunit interface [polypeptide binding].
  
 
 0.917
carB
ATP-grasp domain; cl03087; COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; pfam02787; carbamoyl phosphate synthase large subunit [Lactobacillus coryniformis subsp. coryniformis KCTC 3167]; carbamoyl phosphate synthase large subunit; Reviewed; PRK05294; gene_28; identified by MetaGeneAnnotator; putative.
  
 
 0.914
BAP85638.1
Carbamoyl-phosphate synthase large subunit; Gene_1058; identified by MetaGeneAnnotator; putative.
  
 
 0.914
carB-2
ATP-grasp domain; cl03087; ATP-grasp domain; pfam13535; Carbamoyl-phosphate synthase L chain, N-terminal domain; pfam00289; Carbamoyl-phosphate synthase large chain [Lactobacillus pentosus KCA1]; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; pfam02787; IMP binding site; Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways..; cd01424; carbamoyl phosphate synthase large subunit [...]
  
 
 0.914
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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