node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BAP85731.1 | BAP85736.1 | LOOC260_111920 | LOOC260_111970 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | Hypothetical protein; COG: COG2740; Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; cd00279; gene_1156; identified by MetaGeneAnnotator; putative; nucleic-acid-binding protein implicated in transcription termination [Lactobacillus reuteri MM2- 3]; putative RNA binding cleft [nucleotide binding]. | 0.652 |
BAP85731.1 | BAP86576.1 | LOOC260_111920 | LOOC260_120700 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | Nitroreductase; Gene_1996; identified by MetaGeneAnnotator; putative; Belongs to the flavin oxidoreductase frp family. | 0.918 |
BAP85731.1 | cmk | LOOC260_111920 | LOOC260_111430 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | Cytidylate kinase; CMP-binding site; COG0283 Cytidylate kinase; Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; cd02020; The sites determining sugar specificity; cytidylate kinase [Lactobacillus coryniformis subsp. coryniformis KCTC 3167]; cytidylate kinase; Provisional; PRK00023; gene_1102; identified by MetaGeneAnnotator; putative. | 0.711 |
BAP85731.1 | coaD | LOOC260_111920 | LOOC260_113350 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.756 |
BAP85731.1 | ileS | LOOC260_111920 | LOOC260_113720 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.667 |
BAP85731.1 | infB | LOOC260_111920 | LOOC260_111950 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.699 |
BAP85731.1 | mnmA | LOOC260_111920 | LOOC260_113640 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.654 |
BAP85731.1 | nusA | LOOC260_111920 | LOOC260_111980 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.698 |
BAP85731.1 | rbfA | LOOC260_111920 | LOOC260_111940 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.729 |
BAP85731.1 | truB | LOOC260_111920 | LOOC260_111930 | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.994 |
BAP85736.1 | BAP85731.1 | LOOC260_111970 | LOOC260_111920 | Hypothetical protein; COG: COG2740; Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; cd00279; gene_1156; identified by MetaGeneAnnotator; putative; nucleic-acid-binding protein implicated in transcription termination [Lactobacillus reuteri MM2- 3]; putative RNA binding cleft [nucleotide binding]. | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | 0.652 |
BAP85736.1 | infB | LOOC260_111970 | LOOC260_111950 | Hypothetical protein; COG: COG2740; Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; cd00279; gene_1156; identified by MetaGeneAnnotator; putative; nucleic-acid-binding protein implicated in transcription termination [Lactobacillus reuteri MM2- 3]; putative RNA binding cleft [nucleotide binding]. | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. | 0.974 |
BAP85736.1 | nusA | LOOC260_111970 | LOOC260_111980 | Hypothetical protein; COG: COG2740; Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; cd00279; gene_1156; identified by MetaGeneAnnotator; putative; nucleic-acid-binding protein implicated in transcription termination [Lactobacillus reuteri MM2- 3]; putative RNA binding cleft [nucleotide binding]. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.975 |
BAP85736.1 | rbfA | LOOC260_111970 | LOOC260_111940 | Hypothetical protein; COG: COG2740; Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; cd00279; gene_1156; identified by MetaGeneAnnotator; putative; nucleic-acid-binding protein implicated in transcription termination [Lactobacillus reuteri MM2- 3]; putative RNA binding cleft [nucleotide binding]. | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. | 0.857 |
BAP85736.1 | truB | LOOC260_111970 | LOOC260_111930 | Hypothetical protein; COG: COG2740; Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; cd00279; gene_1156; identified by MetaGeneAnnotator; putative; nucleic-acid-binding protein implicated in transcription termination [Lactobacillus reuteri MM2- 3]; putative RNA binding cleft [nucleotide binding]. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.738 |
BAP86576.1 | BAP85731.1 | LOOC260_120700 | LOOC260_111920 | Nitroreductase; Gene_1996; identified by MetaGeneAnnotator; putative; Belongs to the flavin oxidoreductase frp family. | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | 0.918 |
cmk | BAP85731.1 | LOOC260_111430 | LOOC260_111920 | Cytidylate kinase; CMP-binding site; COG0283 Cytidylate kinase; Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; cd02020; The sites determining sugar specificity; cytidylate kinase [Lactobacillus coryniformis subsp. coryniformis KCTC 3167]; cytidylate kinase; Provisional; PRK00023; gene_1102; identified by MetaGeneAnnotator; putative. | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | 0.711 |
cmk | nusA | LOOC260_111430 | LOOC260_111980 | Cytidylate kinase; CMP-binding site; COG0283 Cytidylate kinase; Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; cd02020; The sites determining sugar specificity; cytidylate kinase [Lactobacillus coryniformis subsp. coryniformis KCTC 3167]; cytidylate kinase; Provisional; PRK00023; gene_1102; identified by MetaGeneAnnotator; putative. | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. | 0.667 |
coaD | BAP85731.1 | LOOC260_113350 | LOOC260_111920 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | 0.756 |
ileS | BAP85731.1 | LOOC260_113720 | LOOC260_111920 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Riboflavin biosynthesis protein RibF; COG: COG0196; FAD synthetase [Lactobacillus vaginalis ATCC 49540]; FAD synthetase, N-terminal domain of the bifunctional enzyme; cd02064; Riboflavin kinase; smart00904; bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; gene_1151; identified by MetaGeneAnnotator; putative; Belongs to the ribF family. | 0.667 |