STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
BAP85840.1PfkB family carbohydrate kinase; 2-dehydro-3-deoxygluconate kinase [Lactobacillus pentosus KCA1]; 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the..; cd01166; ATP binding site [chemical binding]; Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; COG0524; gene_1260; identified by MetaGeneAnnotator; putative; substrate binding site [chemical binding]. (340 aa)    
Predicted Functional Partners:
BAP85316.1
2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; COG0800; KDPG and KHG aldolase; cd00452; catalytic residue [active]; catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; gene_736; identified by MetaGeneAnnotator; putative; intersubunit interface [polypeptide binding]; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Lactobacillus brevis ATCC 367].
 
 0.988
BAP86581.1
2-keto-3-deoxy-6-phosphogluconate aldolase [Carbohydrate transport and metabolism]; COG0800; KDPG and KHG aldolase; cd00452; catalytic residue [active]; catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; gene_2001; identified by MetaGeneAnnotator; putative; intersubunit interface [polypeptide binding]; keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase [Lactobacillus brevis ATCC 367].
 
 0.988
BAP86582.1
2-dehydro-3-deoxygluconokinase [Tetragenococcus halophilus]; 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the..; cd01166; ATP binding site [chemical binding]; ORF08; similar to 2-dehydro-3-deoxygluconokinase of some lactobacilli; Sugar kinases, ribokinase family [Carbohydrate transport and metabolism]; COG0524; gene_2002; identified by MetaGeneAnnotator; putative; substrate binding site [...]
    
 
0.900
uxuA
Mannonate dehydratase; Catalyzes the dehydration of D-mannonate.
 
  
 0.887
rpe
COG0036 [G] Pentose-5-phosphate-3-epimerase; Pentose-5-phosphate-3-epimerase [Carbohydrate transport and metabolism]; COG0036; Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose..; cd00429; gene_995; hexamer interface [polypeptide binding]; identified by MetaGeneAnnotator; putative; metal binding site [ion binding]; ribulose-phosphate 3-epimerase [Lactobacillus salivarius UCC118]; subs [...]
  
 0.874
BAP85315.1
2-deoxy-D-gluconate 3-dehydrogenase [Fusobacterium mortiferum ATCC 9817]; 2-deoxy-D-gluconate 3-dehydrogenase; Provisional; NADP binding site [chemical binding]; gene_735; gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; cd05347; homodimer interface [polypeptide binding]; identified by MetaGeneAnnotator; putative.
  
  0.826
BAP86541.1
2-deoxy-D-gluconate 3-dehydrogenase; Gene_1961; identified by MetaGeneAnnotator; putative.
  
  0.826
BAP86584.1
2-deoxy-D-gluconate 3-dehydrogenase [Clostridium beijerinckii NCIMB 8052]; 2-deoxy-D-gluconate 3-dehydrogenase; Provisional; Involved in the metabolism of 2-deoxyglucose; NADP binding site [chemical binding]; gene_2004; gluconate 5-dehydrogenase (Ga5DH)-like, classical (c) SDRs; cd05347; homodimer interface [polypeptide binding]; identified by MetaGeneAnnotator; putative.
  
  0.826
nagE
PTS N-acetylglucosamine transporter subunit IIABC; COG: COG1263; Pfam: PF02378,PF00367,PF00358; InterPro: IPR010974; HPr interaction site; PTS family N-acetylglucosamine porter, IIABC component [Lactobacillus plantarum subsp. plantarum ATCC 14917]; PTS system, N-acetylglucosamine-specific IIBC component; TIGR01998; PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family..; cd00212; Phosphotr [...]
  
  
 0.683
rbsD
D-ribose pyranase; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.
  
  
 0.531
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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