STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BAP86427.1Alpha-glucosidase; Galactose mutarotase-like; pfam13802; KEGG: lwe:lwe0241 4.0e-244 alpha-xylosidase YicI K01811; YicI alpha-xylosidase is a glycosyl hydrolase family 31 (GH31) enzyme that catalyzes the release of an alpha-xylosyl residue from the non-reducing end of alpha-xyloside substrates such as alpha-xylosyl fluoride and isoprimeverose. YicI forms a..; cd06593; catalytic site [active]; gene_1847; glycosyl hydrolase, family 31 [Lactobacillus kisonensis F0435]; homohexamer (dimer of homotrimers) interface [polypeptide binding]; homotrimer interface [polypeptide binding]; identified [...] (759 aa)    
Predicted Functional Partners:
BAP86425.1
ROK family transcriptional regulator; DNA binding site [nucleotide binding]; KEGG: ret:RHE_CH01552 2.9e-28 ypch00534; ROK family transcriptional regulator; Psort location: Cytoplasmic, score: 9.97; MarR family; pfam12802; Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; cl17037; ROK family protein [Lactobacillus kisonensis F0435]; Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; COG1940; gene_1845; identified by MetaGeneAnnotator; putative; non-specific DNA interactions [nucleotide binding]; putative cAMP binding site [...]
 
  
 0.690
bglA
6-phospho-beta-glucosidase [Lactobacillus rhamnosus GG]; Glycosyl hydrolase family 1; cl01046; gene_1844; identified by MetaGeneAnnotator; putative; strain coidentity: ATCC 53103 = GG; synonym: Lactobacillus rhamnosus ATCC 53103.
 
 
 0.611
BAP86426.1
Putative xylose-proton symporter; KEGG: eci:UTI89_C4210 4.3e-57 yicJ; putative transporter K03292; Psort location: CytoplasmicMembrane, score: 10.00; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of..; cd06174; gene_1846; identified by MetaGeneAnnotator; putative; putative substrate translocation pore; sugar (Glycoside-Pentoside-Hexuronide) transporter; TIGR00792; transporter, major facilitato [...]
  
 0.599
dnaJ
Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...]
   
   0.545
BAP86422.1
Glycosyl hydrolase family 3; Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism]; COG1472; Glycosyl hydrolase family 3 C-terminal domain; pfam01915; Glycosyl hydrolase family 3 N terminal domain; pfam00933; KEGG: ooe:OEOE_1569 9.0e-231 beta-glucosidase-related glycosidase; K05349 beta-glucosidase; Psort location: Periplasmic, score: 9.44; gene_1842; glycosyl hydrolase family 3 protein [Lactobacillus kisonensis F0435]; identified by MetaGeneAnnotator; putative; partial.
 
   
 0.516
BAP86421.1
Glycosyl hydrolase family 3; Gene_1841; identified by MetaGeneAnnotator; putative; partial.
 
   
 0.469
BAP86423.1
ROK family transcriptional regulator; Gene_1843; identified by MetaGeneAnnotator; putative.
  
  
 0.441
BAP86540.1
enoyl-CoA hydratase/isomerase; 3-hydroxybutyryl-CoA dehydratase; Validated; COG1024 Enoyl-CoA hydratase/carnithine racemase; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558; enoyl-CoA hydratase/isomerase [Lactobacillus farciminis KCTC 3681]; gene_1960; identified by MetaGeneAnnotator; putative; oxyanion hole (OAH) forming residues; substrate binding site [chemical binding]; trim [...]
    
 
 0.422
rnc
Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.
   
   0.412
xyrR
Xylose repressor; Gene_1840; identified by MetaGeneAnnotator; putative.
 
  
 0.406
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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