STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
potBABC-ATPase subunit interface; ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism]; COG1176; Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and..; cd06261; conserved gate region; dimer interface [polypeptide binding]; gene_1867; identified by MetaGeneAnnotator; putative; putative PBP binding loops; spermidine/putrescine ABC transpor [...] (269 aa)    
Predicted Functional Partners:
potD
Spermidine/putrescine ABC transporter substrate-binding protein; Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; COG0687; The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; cl11398; gene_1865; identified by MetaGeneAnnotator; putative; lreu_v1_TGAC_scaffold_03; spermidine/putrescine ABC transporter substrate-binding component [Lactobacillus reuteri ATCC 53608].
 
 0.999
potC
ABC-ATPase subunit interface; ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; COG1177; Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and..; cd06261; conserved gate region; dimer interface [polypeptide binding]; gene_1866; identified by MetaGeneAnnotator; putative; putative PBP binding loops; spermidine/putrescine ABC transpo [...]
 
0.999
potA
Spermidine/putrescine ABC transporter ATP-binding protein; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.
 0.999
pepX
X-prolyl-dipeptidyl aminopeptidase; Removes N-terminal dipeptides sequentially from polypeptides having unsubstituted N-termini provided that the penultimate residue is proline; Belongs to the peptidase S15 family.
       0.503
ecfA-2
Cobalt transporter ATP-binding subunit; ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates.
 
 
  
 0.484
BAP84632.1
Sugar ABC transporter ATPase; Gene_52; identified by MetaGeneAnnotator; putative; Belongs to the ABC transporter superfamily.
   
 0.482
murG
UDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily.
   
  
 0.452
BAP85867.1
Competence protein ComEC; Gene_1287; identified by MetaGeneAnnotator; putative.
       0.433
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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