STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
etfAElectron transfer flavoprotein FAD-binding domain; pfam00766; Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; COG2025; KEGG: apb:SAR116_1869 1.1e-26 electron transfer flavoprotein alpha-subunit K03522; The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an..; cd01715; electron transfer flavoprotein FAD-binding domain protein [Lactobacillus kisonensis F0435]; [...] (320 aa)    
Predicted Functional Partners:
BAP86694.1
Acyl-CoA dehydrogenase; cl09933; Acyl-CoA dehydrogenases [Lipid metabolism]; COG1960; KEGG: lbr:LVIS_1909 1.0e-119 acyl-CoA dehydrogenase; K00248 butyryl-CoA dehydrogenase; Psort location: Cytoplasmic, score: 9.97; acyl-CoA dehydrogenase protein [Lactobacillus kisonensis F0435]; gene_2114; identified by MetaGeneAnnotator; putative.
 
 0.999
etfB
Electron transfer flavoprotein domain; pfam01012; Ligand binding site [chemical binding]; The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an..; cd01714; electron transfer flavoprotein subunit beta [Lactobacillus buchneri CD034]; gene_2115; identified by MetaGeneAnnotator; putative.
 0.999
BAP84744.1
COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Rossmann-fold NAD(P)(+)-binding proteins; cl09931; flavocytochrome c; TIGR01813; fumarate reductase flavoprotein subunit [Lactobacillus farciminis KCTC 3681]; gene_164; identified by MetaGeneAnnotator; putative; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.950
BAP86540.1
enoyl-CoA hydratase/isomerase; 3-hydroxybutyryl-CoA dehydratase; Validated; COG1024 Enoyl-CoA hydratase/carnithine racemase; Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; cd06558; enoyl-CoA hydratase/isomerase [Lactobacillus farciminis KCTC 3681]; gene_1960; identified by MetaGeneAnnotator; putative; oxyanion hole (OAH) forming residues; substrate binding site [chemical binding]; trim [...]
 
 0.827
BAP84897.1
NADH-dependent flavin oxidoreductase; NADH:flavin oxydoreductase, Old Yellow Enzyme family [Oenococcus oeni]; ORF11; Oxidored_FMN; pfam 00724; Oye_like_4_FMN; cd04735; Old yellow enzyme (OYE)-related FMN binding domain, group 4. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as..; cd04735; gene_317; identified by MetaGeneAnnotator; putative; putative FMN binding site [chemical binding]; putative active site [active]; putative catalytic residue [acti [...]
   
 
 0.748
BAP86432.1
3-hydroxybutyryl-CoA dehydrogenase; Gene_1852; identified by MetaGeneAnnotator; putative.
  
 
 0.722
adhE
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); cd08178; Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; cd07122; bifunctional acetaldehyde-CoA/alcohol dehydrogenase [Lactobacillus brevis ATCC 367]; bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; gene_1976; identified by MetaGeneAnnotator; putative; metal binding site [ion binding]; putative active site [active]; putative catalytic cysteine [active].
  
 
 0.701
pdhC
Dihydrolipoamide acetyltransferase; 2-oxoacid dehydrogenases acyltransferase (catalytic domain); pfam00198; E3 interaction surface; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid..; cd06849; acetoin/pyruvate dehydrogenase complex, E2 component, dihydrolipoamide succinyltransferase [Lactobacillus brevis ATCC 367]; branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; e3 binding d [...]
   
  
 0.616
nagE
PTS N-acetylglucosamine transporter subunit IIABC; COG: COG1263; Pfam: PF02378,PF00367,PF00358; InterPro: IPR010974; HPr interaction site; PTS family N-acetylglucosamine porter, IIABC component [Lactobacillus plantarum subsp. plantarum ATCC 14917]; PTS system, N-acetylglucosamine-specific IIBC component; TIGR01998; PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family..; cd00212; Phosphotr [...]
   
  
 0.553
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
  
 
 0.541
Your Current Organism:
Lactobacillus hokkaidonensis
NCBI taxonomy Id: 1291742
Other names: L. hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis JCM 18461, Lactobacillus hokkaidonensis LOOC260, Lactobacillus sp. LOOC260
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