STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
GAK47142.1Transcriptional regulator; Gene_240; identified by MetaGeneAnnotator; putative. (318 aa)    
Predicted Functional Partners:
nagE
PTS family N-acetylglucosamine porter, IIABC component; COG: COG1263; Pfam: PF02378,PF00367,PF00358; InterPro: IPR010974; HPr interaction site; PTS family N-acetylglucosamine porter, IIABC component [Lactobacillus plantarum subsp. plantarum ATCC 14917]; PTS system, N-acetylglucosamine-specific IIBC component; TIGR01998; PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family..; cd00212; Phos [...]
  
 
 0.958
GAK47428.1
Pyruvate kinase; Phosphohistidine swiveling domain [Signal transduction mechanisms]; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low..; cd00288; domain interfaces; gene_526; identified by MetaGeneAnnotator; putative; pyruvate kinase [Lactobacillus rhamnosus GG]; pyruvate kinase; Provisional; strain coidentity: ATCC 53103 = GG; synonym: Lactobacillus rhamnosus ATCC 53103.
    
 
 0.802
ptsH
Phosphocarrier protein HPr; COG: COG1925; Pfam: PF00381; InterPro: IPR000032; Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation..; cd00367; PTS family porter, phosphocarrier protein HPR [Lactobacillus helveticus DSM 20075]; dimerization domain swap beta strand [polypeptide binding]; gene_1403; identified by MetaGeneAnnotator; putative; regulatory phosphorylation site [posttranslational [...]
   
 
 0.793
GAK48606.1
Transcriptional regulator; DNA binding site [nucleotide binding]; Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; cd01392; Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR; cd06283; Transcriptional regulators [Transcription]; COG1609; domain linker motif; gene_1704; identified by MetaGeneAnnotator; putative; putative dimerization interface [polypeptide binding]; putative ligand binding site [chemical binding]; transcriptional regulator [Lactobacillus brevis ATCC 367].
  
     0.702
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
    
   0.674
pheT
phenylalanyl-tRNA synthetase beta subunit; B3/4 domain; pfam03483; Ferredoxin-fold anticodon binding domain; pfam03147; Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA, PheRS is an..; cd00769; catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of al [...]
   
   0.603
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily.
    
   0.603
GAK47141.1
DNA binding response regulator [Enterococcus gallinarum EG2]; DNA binding site [nucleotide binding]; Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and..; cd00383; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; COG0745; Signal receiver domain; originally thought to be unique to bacter [...]
       0.568
mapA
Maltose/trehalose phosphorylase; Glycosyl hydrolase family 65 central catalytic domain; pfam03632; Glycosyl hydrolase family 65, C-terminal domain; pfam03633; Glycosyl hydrolase family 65, N-terminal domain; pfam03636; Maltose phosphorylase / Trehalose phosphorylase [Lactobacillus pentosus KCA1]; gene_233; identified by MetaGeneAnnotator; putative; maltose phosphorylase; Provisional.
 
   
 0.504
GAK47414.1
DNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
   
 
 0.496
Your Current Organism:
Lactobacillus oryzae
NCBI taxonomy Id: 1291743
Other names: L. oryzae JCM 18671, Lactobacillus oryzae JCM 18671, Lactobacillus oryzae SG293, Lactobacillus sp. JCM 18671, Lactobacillus sp. SG293
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